According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

This manuscript provides a comprehensive review of the peptide and protein identification
process using tandem mass spectrometry (MS/MS) data generated in shotgun proteomic …

Because of its availability, ease of collection, and correlation with physiology and pathology,
urine is an attractive source for clinical proteomics/peptidomics. However, the lack of …

Large-scale protein sequencing methods rely on enzymatic digestion of complex protein
mixtures to generate a collection of peptides for mass spectrometric analysis. Here we …

(MS) and MS-driven proteomics have continued to develop as the premier tools for
characterizing proteome composition, structure, and function. 2 The new era of proteomics …

Inevitable byproducts of aerobic metabolism are free radicals and other highly reactive
oxidants and nitrosants that are continuously formed within cells. Most cells generally …

Campylobacter jejuni is a gastrointestinal pathogen that is able to modify membrane and
periplasmic proteins by the N-linked addition of a 7-residue glycan at the strict attachment …

Acinetobacter baumannii is an emerging cause of nosocomial infections. The isolation of
strains resistant to multiple antibiotics is increasing at alarming rates. Although A. baumannii …

Recent emergence of new mass spectrometry techniques (eg electron transfer dissociation,
ETD) and improved availability of additional proteases (eg Lys-N) for protein digestion in …

Combining high-mass-accuracy mass spectrometry, isobaric tagging and software for
multiplexed, large-scale protein quantification, we report deep proteomic coverage of four …