The family of mitogen-activated protein kinases (MAPKs) consists of fourteen members and
has been implicated in regulation of virtually all cellular processes. MAPKs are divided into …

Cutaneous melanoma accounts for only about 7% of skin cancers but is causing almost 90%
of deaths. Melanoma cells have a distinct repertoire of mutations from other cancers, a high …

Morinda citrifolia is a traditional plant used in Asian and African countries for its wide
nutraceutical and therapeutic effects for the treatment of various ailments. The fruit of M …

Spice-rich recipes are referred to as “functional foods” because they include a variety of
bioactive chemicals that have health-promoting properties, in addition to their nutritional …

Abstract Alzheimer's disease (AD), a progressive neurodegenerative disorder, manifests as
accumulation of amyloid-beta-42 (Aβ42) plaques and intracellular accumulation of …

The actin cytoskeleton is tightly controlled by RhoGTPases, actin binding-proteins and
nucleation-promoting factors to perform fundamental cellular functions. We have previously …

Mitogen-activated protein kinase (MAPK) cascades are evolutionarily conserved signaling
pathways that play essential roles in transducing extracellular environmental signals into …

Extracellular signal-regulated kinase 3 (ERK3) is an atypical member of the mitogen-
activated protein kinase (MAPK) family, members of which play essential roles in diverse …

Mitogen-activated protein kinase 6 (MAPK6) is an atypical MAPK. Its function in regulating
cancer growth remains elusive. Here, we reported that MAPK6 directly activated AKT and …

Objective Epilepsy causes physical and mental damage to patients. As well known,
microRNAs (miRNAs) provide therapeutic target potentials for patients with epilepsy. miR …