Small and long non-coding RNAs as functional regulators of bone homeostasis, acting alone or cooperatively
Emerging knowledge indicates that non-coding RNAs, including microRNAs (miRNAs) and
long-noncoding RNAs (lncRNAs), have a pivotal role in bone development and the …
long-noncoding RNAs (lncRNAs), have a pivotal role in bone development and the …
Systems analysis of miRNA biomarkers to inform drug safety
AL Schofield, JP Brown, J Brown, A Wilczynska… - Archives of …, 2021 - Springer
Abstract microRNAs (miRNAs or miRs) are short non-coding RNA molecules which have
been shown to be dysregulated and released into the extracellular milieu as a result of many …
been shown to be dysregulated and released into the extracellular milieu as a result of many …
The PGC-1α/NRF1/miR-378a axis protects vascular smooth muscle cells from FFA-induced proliferation, migration and inflammation in atherosclerosis
H Chong, Z Wei, M Na, G Sun, S Zheng, X Zhu, Y Xue… - Atherosclerosis, 2020 - Elsevier
Background and aims Atherosclerosis (AS) is the leading cause of cardiovascular diseases.
PGC-1α is a key regulator of cellular energy homeostasis, but its role in AS remains …
PGC-1α is a key regulator of cellular energy homeostasis, but its role in AS remains …
An Evaluation of the Fasciola hepatica miRnome Predicts a Targeted Regulation of Mammalian Innate Immune Responses
Understanding mechanisms by which parasitic worms (helminths) control their hosts'
immune responses is critical to the development of effective new disease interventions …
immune responses is critical to the development of effective new disease interventions …
miRNome Profiling and Functional Analysis Reveal Involvement of hsa-miR-1246 in Colon Adenoma-Carcinoma Transition by Targeting AXIN2 and CFTR
Regulatory changes occurring early in colorectal cancer development remain poorly
investigated. Since the majority of cases develop from polyps in the adenoma-carcinoma …
investigated. Since the majority of cases develop from polyps in the adenoma-carcinoma …
Noncoding RNAs in apoptosis: identification and function
Apoptosis is a vital cellular process that is critical for the maintenance of homeostasis in
health and disease. The derailment of apoptotic mechanisms has severe consequences …
health and disease. The derailment of apoptotic mechanisms has severe consequences …
Comprehensive analysis of the isomiRome in the vegetative organs of the conifer Pinus pinaster under contrasting water availability
An increasing number of microRNAs (miRNAs) and miRNA‐related sequences produced
during miRNA biogenesis, comprising the isomiRome, have been recently highlighted in …
during miRNA biogenesis, comprising the isomiRome, have been recently highlighted in …
A critical approach for successful use of circulating microRNAs as biomarkers in cardiovascular diseases: the case of hypertrophic cardiomyopathy
MicroRNAs (miRNAs) are small noncoding RNA molecules that act as major regulators of
gene expression at the post-transcriptional level. As the potential applications of miRNAs in …
gene expression at the post-transcriptional level. As the potential applications of miRNAs in …
[HTML][HTML] Commercially available blocking oligonucleotides effectively suppress unwanted hemolysis-related miRNAs in a large whole-blood RNA cohort
J LaBelle, M Bowser, A Brown, L Farnam, A Kho… - The Journal of Molecular …, 2021 - Elsevier
When sequencing small RNA libraries derived from whole blood, the most abundant
microRNAs (miRs) detected are often miR-486-5p, miR-451a, and miR-92a-3p. These …
microRNAs (miRs) detected are often miR-486-5p, miR-451a, and miR-92a-3p. These …
Case report: Micro-RNAs in plasma from bilateral inferior petrosal sinus sampling and peripheral blood from corticotroph pituitary neuroendocrine tumors
H Niedra, R Peculis, I Konrade, I Balcere… - Frontiers in …, 2022 - frontiersin.org
Objective Circulating miRNAs are found in bodily fluids including plasma and can serve as
biomarkers for diseases. The aim of this study was to provide the first insight into the …
biomarkers for diseases. The aim of this study was to provide the first insight into the …