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Current and emerging drug therapies for connective tissue disease-interstitial lung disease (CTD-ILD)
AS Jee, TJ Corte - Drugs, 2019 - Springer
Interstitial lung disease (ILD) can be associated with all connective tissue diseases and is an
important cause of morbidity and mortality. The management of connective tissue disease …
important cause of morbidity and mortality. The management of connective tissue disease …
Interstitial lung disease in systemic sclerosis: focus on early detection and intervention
A Fischer, NM Patel, ER Volkmann - Open access rheumatology …, 2019 - Taylor & Francis
Systemic sclerosis (SSc) is a progressive and often devastating disease characterized by
autoimmune dysfunction, vasculopathy, and fibrosis. Interstitial lung disease (ILD) is …
autoimmune dysfunction, vasculopathy, and fibrosis. Interstitial lung disease (ILD) is …
GPCR-induced YAP activation sensitizes fibroblasts to profibrotic activity of TGFβ1
K Zmajkovicova, Y Bauer, K Menyhart… - PLoS …, 2020 - journals.plos.org
Tissue fibrosis is a pathological condition characterized by uncontrolled fibroblast activation
that ultimately leads to organ failure. The TGFβ1 pathway, one of the major players in …
that ultimately leads to organ failure. The TGFβ1 pathway, one of the major players in …
[HTML][HTML] Thrombin upregulates PAI-1 and mesothelial–mesenchymal transition through PAR-1 and contributes to tuberculous pleural fibrosis
CY Hsieh, JR Sheu, CH Yang, WL Chen… - International journal of …, 2019 - mdpi.com
Thrombin is an essential procoagulant and profibrotic mediator. However, its implication in
tuberculous pleural effusion (TBPE) remains unknown. The effusion thrombin and …
tuberculous pleural effusion (TBPE) remains unknown. The effusion thrombin and …
Heart Failure with Preserved Ejection Fraction and Cardiomyopathy: an Under-recognized Complication of Systemic Sclerosis
Abstract Purpose of Review Heart failure with preserved ejection fraction (HFpEF) and
diastolic dysfunction are major sequelae of primary cardiac disease in patients with systemic …
diastolic dysfunction are major sequelae of primary cardiac disease in patients with systemic …
Autoimmunity in interstitial lung disease
G Sambataro, D Sambataro, V Adiletta… - Translational …, 2022 - Elsevier
Interstitial lung disease (ILD) is one of the most common causes of death in connective
tissue disease (CTD) and vasculitis. The physiological mechanism is not yet fully understood …
tissue disease (CTD) and vasculitis. The physiological mechanism is not yet fully understood …
Scleroderma-associated interstitial lung disease–new therapeutic approach
V Pencheva - Rheumatology (Bulgaria), 2020 - rheumatologybg.org
Scleroderma is a systematic autoimmune disease characterized by endothelial dysfunction
which causes small vessel disease, fibroblastic disorder with excessive production of …
which causes small vessel disease, fibroblastic disorder with excessive production of …