Macrophages form a crucial component of the innate immune system, and their activation is
indispensable for various aspects of immune and inflammatory processes, tissue repair, and …

Ferroptosis, a distinct form of cell death, is characterized by the iron-mediated oxidation of
lipids and is finely controlled by multiple cellular metabolic pathways. These pathways …

Retinal degeneration, characterized by the progressive loss of retinal neurons, is the leading
cause of incurable visual impairment. Retinal progenitor cells (RPCs)‐based transplantation …

Background Retinitis pigmentosa is the prevailing genetic cause of blindness in developed
nations with no effective treatments. In the pursuit of unraveling the intricate dynamics …

Purpose: Neuroinflammation is a characteristic feature of neurodegenerative diseases.
Mesenchymal stem cell-derived exosomes (MSC-exo) have shown neuroprotective effects …

We introduce drexml, a command line tool and Python package for rational data-driven drug
repurposing. The package employs machine learning and mechanistic signal transduction …

Retinitis pigmentosa (RP) is a degenerative disease, caused by genetic mutations that lead
to a loss in photoreceptors. For research on RP, rd10 mice, which carry mutations in the …

Vascular dementia (VaD) causes progressive cognitive decline in the elderly population, but
there is short of available therapeutic measures. Microglia-mediated neuroinflammation is …