Ethosomes as nanocarriers for the development of skin delivery formulations

AC Paiva-Santos, AL Silva, C Guerra, D Peixoto… - Pharmaceutical …, 2021 - Springer
The use of nanotechnology has been extensively explored for develo** efficient drug
delivery systems towards topical and transdermal applications. Ethosomes constitute a …

Nano-formulations for transdermal drug delivery: A review

X Zhou, Y Hao, L Yuan, S Pradhan, K Shrestha… - Chinese Chemical …, 2018 - Elsevier
Transdermal drug delivery refers to a means of delivering drugs through the surface of the
skin for local or systemic treatment. The drug functions after absorption through the skin into …

Central composite design for the development of carvedilol-loaded transdermal ethosomal hydrogel for extended and enhanced anti-hypertensive effect

PR Amarachinta, G Sharma, N Samed… - Journal of …, 2021 - Springer
Background Carvedilol, the anti-hypertensive drug, has poor bioavailability when
administered orally. Ethosomes-mediated transdermal delivery is considered a potential …

[HTML][HTML] Novel transethosomal gel containing miconazole nitrate; development, characterization, and enhanced antifungal activity

Z Asghar, T Jamshaid, M Sajid-ur-Rehman… - Pharmaceutics, 2023 - mdpi.com
Miconazole nitrate (MCNR) is a BCS class II antifungal drug with poor water solubility.
Although numerous attempts have been made to increase its solubility, formulation …

[HTML][HTML] Lipid-based nanovesicular drug delivery systems

T Limongi, F Susa, M Marini, M Allione, B Torre… - Nanomaterials, 2021 - mdpi.com
In designing a new drug, considering the preferred route of administration, various
requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a …

Development and in-vitro evaluation of co-loaded berberine chloride and evodiamine ethosomes for treatment of melanoma

H Lin, L Lin, Y Choi, B Michniak-Kohn - International journal of …, 2020 - Elsevier
Berberine chloride (BBR) and evodiamine (EVO) are two main active ingredients of
“Zuo**Wan”, a classical Chinese herbal medicine, and these compounds are known to …

Transdermal drug delivery: Opportunities and challenges for controlled delivery of therapeutic agents using nanocarriers

B Das Kurmi, P Tekchandani, R Paliwal… - Current drug …, 2017 - ingentaconnect.com
Background: Transdermal drug delivery represents an extremely attractive and innovative
route across the skin owing to the possibility for achieving systemic effect of drugs. The …

Mechanism of transdermal permeation promotion of lipophilic drugs by ethosomes

L Yang, L Wu, D Wu, D Shi, T Wang… - International journal of …, 2017 - Taylor & Francis
Ethosomes can promote the penetration of lipophilic drugs into the skin, but the underlying
mechanism is still unknown. The purpose of this study was to investigate the mechanism of …

Transcutaneous tumor vaccination combined with anti-programmed death-1 monoclonal antibody treatment produces a synergistic antitumor effect

X Song, Y Jiang, W Zhang, G Elfawal, K Wang, D Jiang… - Acta biomaterialia, 2022 - Elsevier
Transcutaneous immunization (TCI) has the advantages of safety, high efficiency, non-
invasiveness and convenient use. The key for a TCI system is transdermal targeted delivery …

[HTML][HTML] Statistical optimization of tetrahydrocurcumin loaded solid lipid nanoparticles using Box Behnken design in the management of streptozotocin-induced …

JB Sharma, S Bhatt, A Tiwari, V Tiwari, M Kumar… - Saudi Pharmaceutical …, 2023 - Elsevier
In the past, curcumin was the go-to medication for diabetes, but recent studies have shown
that tetrahydrocurcumin is more effective. The problem is that it's not very soluble in water or …