It remains a challenge for the effective treatment of neuroinflammatory disease, including
multiple sclerosis (MS), stroke, epilepsy, and Alzheimer's and Parkinson's disease. The …

The CAP protein superfamily (Cysteine-rich secretory proteins (CRISPs), Antigen 5 (Ag5),
and Pathogenesis-related 1 (PR-1) proteins) is widely distributed, but for toxinologists …

This article provides a brief overview of the literature related to the chemical ecology of sea
anemones, focusing on their venom, and summarizing their bioprospecting potential. Sea …

Toxins from marine animals provide molecular tools for the study of many ion channels,
including mammalian voltage-gated potassium channels of the Kv1 family. Selectivity …

Abstract Background The ShK toxin from Stichodactyla helianthus has established the
therapeutic potential of sea anemone venom peptides, but many lineage-specific toxin …

Bioactive compounds are abundant in animals originating from marine ecosystems. Ion
channels, which include sodium, potassium, calcium, and chloride, together with their …

Tube anemones, or cerianthids, are a phylogenetically informative group of cnidarians with
complex life histories, including a pelagic larval stage and tube-dwelling adult stage, both …

Voltage-gated sodium channels (VGSCs) are considered to be one of the most important ion
channels given their remarkable physiological role. VGSCs constitute a family of large …

The sea anemone Nematostella vectensis (Anthozoa, Cnidaria) is a powerful model for
characterizing the evolution of genes functioning in venom and nervous systems. Although …

Sea anemone venom is a marine drug resource library with pharmacological and
biotechnology value, and it contains complex and diverse functional peptide neurotoxins …