Fatty acid metabolism is known to support tumorigenesis and disease progression as well
as treatment resistance through enhanced lipid synthesis, storage and catabolism. More …

Chemokines are a family of small cytokines, which guide a variety of immune/inflammatory
cells to the site of tumor in tumorigenesis. A dysregulated expression of chemokines is …

Obesity has been linked to the increased risk and aggressiveness of many types of
carcinoma. A state of chronic inflammation in adipose tissue (AT), resulting in genotoxic …

Solid tumor growth and metastasis require the interaction of tumor cells with the surrounding
tissue, leading to a view of tumors as tissue-level phenomena rather than exclusively cell …

Obesity favours the occurrence of locally disseminated prostate cancer in the periprostatic
adipose tissue (PPAT) surrounding the prostate gland. Here we show that adipocytes from …

Obesity is known to have important roles in driving prostate cancer aggressiveness and
increased mortality. Multiple mechanisms have been postulated for these clinical …

Prostate cancer (PCa) is the most common male malignancy and the fifth leading cause of
cancer death in men worldwide. Prostate cancer cells are characterized by a hybrid …

As one of novel hallmarks of cancer, lipid metabolic reprogramming has recently been
becoming fascinating and widely studied. Lipid metabolic reprogramming in cancer is …

Prostate gland is surrounded by periprostatic adipose tissue (PPAT), which is increasingly
believed to play a paracrine role in prostate cancer progression. Our previous work …

Simple Summary Cholesterol, lipids, and lipid metabolism are important in prostate cancer.
Lipid metabolism interacts with androgens which are of clear importance in prostate cancer …