Pemphigus is a severe autoimmune disease impairing barrier functions of epidermis and
mucosa. Autoantibodies primarily target the desmosomal adhesion molecules desmoglein …

Pemphigus vulgaris (PV) is a potentially life-threatening blistering disorder characterized by
autoantibodies directed against cell-cell adhesion molecules that serves as an excellent …

Binding of autoantibodies to keratinocyte surface antigens, primarily desmoglein 3 (Dsg3) of
the desmosomal complex, leads to the dissociation of cell-cell adhesion in the blistering …

Desmosomes play a crucial role in maintaining tissue barrier integrity, particularly in
mechanically stressed tissues. The assembly of desmosomes is regulated by the …

A current challenge in 3D bioprinting of skin equivalents is to recreate the distinct basal and
suprabasal layers and promote their direct interactions. Such a structural arrangement is …

Desmosomes are specialized cell-cell junctions that play a critical role in maintaining tissue
barrier integrity, particularly in mechanically stressed tissues. The assembly of desmosomes …

Epithelial cells experience long lasting loads of different magnitudes and rates. How they
adapt to these loads strongly impacts tissue health. Yet, much remains unknown about their …

Pemphigus vulgaris (PV) is a blistering autoimmune disease that affects the skin and
mucous membranes. The precise mechanisms by which PV antibodies induce a complete …

Binding of autoantibodies to keratinocyte surface antigens, primarily desmoglein 3 (Dsg3) of
the desmosomal complex, leads to the dissociation of cell-cell adhesion in the blistering …