Organisms are constantly exposed to microbial pathogens in their environments. When a
pathogen meets its host, a series of intricate intracellular interactions shape the outcome of …

Ticks are efficient vectors of arboviruses, although less than 10% of tick species are known
to be virus vectors. Most tick-borne viruses (TBV) are RNA viruses some of which cause …

Ixodes spp. and related ticks transmit prevalent infections, although knowledge of their
biology and development of anti-tick measures have been hindered by the lack of a high …

Ticks transmit more pathogens to humans and animals than any other arthropod. We
describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors …

Flaviviruses have an intimate relationship with their host cells, utilizing host proteins during
replication. Much of viral genome replication and virion assembly occurs on and within the …

Background: The tick cell line ISE6, derived from Ixodes scapularis, is commonly used for
amplification and detection of arboviruses in environmental or clinical samples. Methods: To …

The first tick genome published in 2016 provided an invaluable tool for studying the
molecular basis of tick–pathogen interactions. Metabolism is a key element in host …

Tick cell lines are increasingly used in many fields of tick and tick-borne disease research.
The Tick Cell Biobank was established in 2009 to facilitate the development and uptake of …

Background There has been an emergence and expansion of tick-borne diseases in
Europe, Asia and North America in recent years, including Lyme disease, tick-borne …

Sequences of the genomes of all-important bacterial pathogens of man, plants, and animals
have been completed. Still, it is not enough to achieve complete information of all the …