Charting the genotype–phenotype map: lessons from the Drosophila melanogaster Genetic Reference Panel
TFC Mackay, W Huang - Wiley Interdisciplinary Reviews …, 2018 - Wiley Online Library
Understanding the genetic architecture (causal molecular variants, their effects, and
frequencies) of quantitative traits is important for precision agriculture and medicine and …
frequencies) of quantitative traits is important for precision agriculture and medicine and …
Shedding Light on Inter-Individual Variability of Olfactory Circuits in Drosophila
K Rihani, S Sachse - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
Inter-individual differences in behavioral responses, anatomy or functional properties of
neuronal populations of animals having the same genotype were for a long time …
neuronal populations of animals having the same genotype were for a long time …
Stochasticity, individuality and behavior
No two individuals are exactly alike. More than a simple platitude, this observation reflects
the fundamentally stochastic nature of biological systems. The term 'stochastic'describes …
the fundamentally stochastic nature of biological systems. The term 'stochastic'describes …
Viruses in Laboratory Drosophila and Their Impact on Host Gene Expression
O Kuyateh, DJ Obbard - Viruses, 2023 - mdpi.com
Drosophila melanogaster has one of the best characterized antiviral immune responses
among invertebrates. However, relatively few easily transmitted natural virus isolates are …
among invertebrates. However, relatively few easily transmitted natural virus isolates are …
The structure of behavioral variation within a genotype
Z Werkhoven, A Bravin, K Skutt-Kakaria, P Reimers… - Elife, 2021 - elifesciences.org
Individual animals vary in their behaviors. This is true even when they share the same
genotype and were reared in the same environment. Clusters of covarying behaviors …
genotype and were reared in the same environment. Clusters of covarying behaviors …
Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster
Circadian rhythms influence physiological processes from sleep–wake cycles to body
temperature and are controlled by highly conserved cycling molecules. Although the …
temperature and are controlled by highly conserved cycling molecules. Although the …
Transcriptome diversity is a systematic source of variation in RNA-sequencing data
PE García-Nieto, B Wang… - PLoS Computational …, 2022 - journals.plos.org
RNA sequencing has been widely used as an essential tool to probe gene expression.
While standard practices have been established to analyze RNA-seq data, it is still …
While standard practices have been established to analyze RNA-seq data, it is still …
Using single‐plant‐omics in the field to link maize genes to functions and phenotypes
Most of our current knowledge on plant molecular biology is based on experiments in
controlled laboratory environments. However, translating this knowledge from the laboratory …
controlled laboratory environments. However, translating this knowledge from the laboratory …
Widespread inter‐individual gene expression variability in Arabidopsis thaliana
S Cortijo, Z Aydin, S Ahnert… - Molecular systems biology, 2019 - embopress.org
A fundamental question in biology is how gene expression is regulated to give rise to a
phenotype. However, transcriptional variability is rarely considered although it could …
phenotype. However, transcriptional variability is rarely considered although it could …
An Integrated Database for Exploring Alternative Promoters in Animals
F Xue, Y Yan, W **, H Zhu, Y Yang, Z Yu, X Xu… - Scientific Data, 2025 - nature.com
Alternative promoter (AP) events, as a major pre-transcriptional mechanism, can initiate
different transcription start sites to generate distinct mRNA isoforms and regulate their …
different transcription start sites to generate distinct mRNA isoforms and regulate their …