An overview of animal prion diseases

M Imran, S Mahmood - Virology journal, 2011 - Springer
Prion diseases are transmissible neurodegenerative conditions affecting human and a wide
range of animal species. The pathogenesis of prion diseases is associated with the …

A review of selected genes with known effects on performance and health of cattle

E Casas, ME Kehrli Jr - Frontiers in veterinary science, 2016 - frontiersin.org
There are genetic conditions that influence production in dairy and beef cattle. The objective
of this review was to describe relevant genetic conditions that have been associated with …

SNPs for parentage testing and traceability in globally diverse breeds of sheep

MP Heaton, KA Leymaster, TS Kalbfleisch, JW Kijas… - PloS one, 2014 - journals.plos.org
DNA-based parentage determination accelerates genetic improvement in sheep by
increasing pedigree accuracy. Single nucleotide polymorphism (SNP) markers can be used …

[PDF][PDF] Continuous chromosome-scale haplotypes assembled from a single interspecies F1 hybrid of yak and cattle

ES Rice, S Koren, A Rhie, MP Heaton… - …, 2020 - academic.oup.com
Background The development of trio binning as an approach for assembling diploid
genomes has enabled the creation of fully haplotype-resolved reference genomes. Unlike …

Colonialism in South Africa leaves a lasting legacy of reduced genetic diversity in Cape buffalo

L Quinn, G Garcia‐Erill, C Santander… - Molecular …, 2023 - Wiley Online Library
The iconic Cape buffalo has experienced several documented population declines in recent
history. These declines have been largely attributed to the late 19th century rinderpest …

BSE case associated with prion protein gene mutation

JA Richt, SM Hall - PLoS Pathogens, 2008 - journals.plos.org
Bovine spongiform encephalopathy (BSE) is a transmissible spongiform encephalopathy
(TSE) of cattle and was first detected in 1986 in the United Kingdom. It is the most likely …

P6026 Using diverse US beef cattle genomes to identify missense mutations in EPAS1, a gene associated with high-altitude pulmonary hypertension

MP Heaton, TPL Smith, JK Carnahan… - Journal of Animal …, 2016 - academic.oup.com
The availability of whole genome sequence (WGS) data has made it possible to discover
protein variants in silico. However, bovine WGS databases comprised of related influential …

Association of ARRDC3 and NFIA variants with bovine congestive heart failure in feedlot cattle

MP Heaton, GP Harhay, AS Bassett, HJ Clark… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background Bovine congestive heart failure (BCHF) has become increasingly prevalent
among feedlot cattle in the Western Great Plains of North America with up to 7% mortality in …

Atypical prion diseases in humans and animals

MA Tranulis, SL Benestad, T Baron, H Kretzschmar - Prion Proteins, 2011 - Springer
Although prion diseases, such as Creutzfeldt–Jakob disease (CJD) in humans and scrapie
in sheep, have long been recognized, our understanding of their epidemiology and …

Bovine spongiform encephalopathy

JL Harman, CJ Silva - Journal of the American Veterinary …, 2009 - Am Vet Med Assoc
Disease-causing prions and the normal native prion proteins have identical amino acid
sequences and differ only in their folding pattern or conformation (ie, they are isoforms). 47 …