Exploring tissue architecture using spatial transcriptomics
Spatial transcriptomics (ST) technologies generate multiple data types from biological
samples, namely gene expression, physical distance between data points, and/or tissue …
samples, namely gene expression, physical distance between data points, and/or tissue …
Molecularly defined and spatially resolved cell atlas of the whole mouse brain
In mammalian brains, millions to billions of cells form complex interaction networks to enable
a wide range of functions. The enormous diversity and intricate organization of cells have …
a wide range of functions. The enormous diversity and intricate organization of cells have …
Museum of spatial transcriptomics
The function of many biological systems, such as embryos, liver lobules, intestinal villi, and
tumors, depends on the spatial organization of their cells. In the past decade, high …
tumors, depends on the spatial organization of their cells. In the past decade, high …
Spatial-CUT&Tag: spatially resolved chromatin modification profiling at the cellular level
Spatial omics emerged as a new frontier of biological and biomedical research. Here, we
present spatial-CUT&Tag for spatially resolved genome-wide profiling of histone …
present spatial-CUT&Tag for spatially resolved genome-wide profiling of histone …
Systematic comparison of sequencing-based spatial transcriptomic methods
Y You, Y Fu, L Li, Z Zhang, S Jia, S Lu, W Ren, Y Liu… - Nature …, 2024 - nature.com
Recent developments of sequencing-based spatial transcriptomics (sST) have catalyzed
important advancements by facilitating transcriptome-scale spatial gene expression …
important advancements by facilitating transcriptome-scale spatial gene expression …
The role of m6A modification in the biological functions and diseases
X Jiang, B Liu, Z Nie, L Duan, Q **ong, Z **… - Signal transduction and …, 2021 - nature.com
Abstract N6-methyladenosine (m6A) is the most prevalent, abundant and conserved internal
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays
Spatially resolved transcriptomic technologies are promising tools to study complex
biological processes such as mammalian embryogenesis. However, the imbalance between …
biological processes such as mammalian embryogenesis. However, the imbalance between …
HypoMap—a unified single-cell gene expression atlas of the murine hypothalamus
The hypothalamus plays a key role in coordinating fundamental body functions. Despite
recent progress in single-cell technologies, a unified catalog and molecular characterization …
recent progress in single-cell technologies, a unified catalog and molecular characterization …