The effects of chronic stress on the human brain: From neurotoxicity, to vulnerability, to opportunity
For the last five decades, science has managed to delineate the mechanisms by which
stress hormones can impact on the human brain. Receptors for glucocorticoids are found in …
stress hormones can impact on the human brain. Receptors for glucocorticoids are found in …
A users guide to HPA axis research
Glucocorticoid hormones (cortisol and corticosterone-CORT) are the effector hormones of
the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic …
the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic …
[HTML][HTML] Physiological feelings
EF Pace-Schott, MC Amole, T Aue, M Balconi… - Neuroscience & …, 2019 - Elsevier
The role of peripheral physiology in the experience of emotion has been debated since the
19th century following the seminal proposal by William James that somatic responses to …
19th century following the seminal proposal by William James that somatic responses to …
How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions
RM Sapolsky, LM Romero, AU Munck - Endocrine reviews, 2000 - academic.oup.com
The secretion of glucocorticoids (GCs) is a classic endocrine response to stress. Despite
that, it remains controversial as to what purpose GCs serve at such times. One view …
that, it remains controversial as to what purpose GCs serve at such times. One view …
Protective and damaging effects of stress mediators
BS McEwen - New England journal of medicine, 1998 - Mass Medical Soc
Over 60 years ago, Selye1 recognized the paradox that the physiologic systems activated by
stress can not only protect and restore but also damage the body. What links these …
stress can not only protect and restore but also damage the body. What links these …
Socioeconomic status and health: the challenge of the gradient.
SES is consistently associated with health outcomes, yet little is known about the
psychosocial and behavioral mechanisms that might explain this association. Researchers …
psychosocial and behavioral mechanisms that might explain this association. Researchers …
Physiology and neurobiology of stress and adaptation: central role of the brain
BS McEwen - Physiological reviews, 2007 - journals.physiology.org
The brain is the key organ of the response to stress because it determines what is
threatening and, therefore, potentially stressful, as well as the physiological and behavioral …
threatening and, therefore, potentially stressful, as well as the physiological and behavioral …
Chronic stress and glucocorticoids: from neuronal plasticity to neurodegeneration
Stress and stress hormones, glucocorticoids (GCs), exert widespread actions in central
nervous system, ranging from the regulation of gene transcription, cellular signaling …
nervous system, ranging from the regulation of gene transcription, cellular signaling …
Cognitive and affective development in adolescence
L Steinberg - Trends in cognitive sciences, 2005 - cell.com
Questions about the nature of normative and atypical development in adolescence have
taken on special significance in the last few years, as scientists have begun to recast old …
taken on special significance in the last few years, as scientists have begun to recast old …
Brain corticosteroid receptor balance in health and disease
ER De Kloet, E Vreugdenhil, MS Oitzl… - Endocrine …, 1998 - academic.oup.com
Brain Corticosteroid Receptor Balance in Health and Disease* | Endocrine Reviews | Oxford
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