Biofilm describes a microbially-derived sessile community in which microbial cells are firmly
attached to the substratum and embedded in extracellular polymeric matrix. Microbial …

Biofilms are of great importance in infection control and healthcare-associated infections
owing to their inherent tolerance and 'resistance'to antimicrobial therapies. Biofilms have …

Biofilms cause chronic infections in tissues or by develo** on the surfaces of medical
devices. Biofilm infections persist despite both antibiotic therapy and the innate and adaptive …

Ventilator-associated pneumonia (VAP) affects up to 20% of critically ill patients and induces
significant antibiotic prescription pressure, accounting for half of all antibiotic use in the ICU …

Pseudomonas aeruginosa is a ubiquitous organism that is the focus of intense research
because of its prominent role in disease. Due to its relatively large genome and flexible …

Fungi and bacteria encounter each other in various niches of the human body. There, they
interact directly with one another or indirectly via the host response. In both cases …

EXECUTIVE SUMMARY Since the initial 1996 American Thoracic Society (ATS) guideline
on nosocomial pneumonia, a number of new developments have appeared, mandating a …

Like all sessile organisms, surface-attached communities of bacteria known as biofilms must
release and disperse cells into the environment to colonize new sites. For many pathogenic …

Pathogenic fungi in the genus Candida can cause both superficial and serious systemic
disease, and are now recognized as major agents of hospital-acquired infection. Many …

Whether it is in the setting of disease or in a healthy state, the human body contains a
diverse range of microorganisms, including bacteria and fungi. The interactions between …