Abstract Process Systems Engineering (PSE) is the scientific discipline of integrating scales
and components describing the behavior of a physicochemical system, via mathematical …

Enterprise-wide sustainability involves aspects from molecular-scale design to macroscale
facilities. Typically, these aspects are treated as independent sub-problems. Maintaining …

The competitive, profitable, and safe operation of chemical plants depends on tight and
effective coordination among the different decision making levels of the enterprise, including …

Bayesian optimization (BO) is a powerful technology for optimizing noisy expensive-to-
evaluate black-box functions, with a broad range of real-world applications in science …

In this article, the importance of considering operability and control criteria in the analysis
and design of intensified and modular processes is discussed. We first analyze the impact …

The inevitable presence of uncertain parameters in critical applications of process
optimization can lead to undesirable or infeasible solutions. For this reason, optimization …

Extreme events cause significant damage and disruption to the manufacturing sector,
associated supply chains, and adjacent communities. These disastrous shocks may include …

We present a detailed dynamic model for a reactive distillation system, based on which we
develop design-dependent explicit optimal control strategies. A mixed-integer dynamic …

Historically, process control, process scheduling, and process operational functions (such as
safety and maintenance) have been considered independently, in isolation, and/or in a …

Process Intensification (PI) is a vast and growing area in Chemical Engineering, which deals
with the enhancement of current technology to enable improved efficiency; energy, cost, and …