The field of tissue engineering continues to expand and mature, and several products are
now in clinical use, with numerous other preclinical and clinical studies underway. However …

The principal goal of the FEBio project is to provide an advanced finite element tool for the
biomechanics and biophysics communities that allows researchers to model mechanics …

We present a novel algorithm combined with computational modeling to simulate the
development of knee osteoarthritis. The degeneration algorithm was based on excessive …

Animal cells have served as highly controllable model systems for furthering cartilage tissue
engineering practices in pursuit of treating osteoarthritis. Although successful strategies for …

Tissue growth and remodeling (G&R) is often central to disease etiology and progression, so
understanding G&R is essential for understanding disease and develo** effective …

Economic costs of osteoarthritis (OA) are considerable. However, there are no clinical tools
to predict the progression of OA or guide patients to a correct treatment for preventing OA …

Like all other materials, biological soft tissues are subject to general laws of physics,
including those governing mechanical equilibrium and stability. In addition, however, these …

There is significant interest in modeling the mechanics and physics of growth of soft
biological systems such as tumors and bacterial biofilms. Solid tumors account for more than …

The mechanics of biological fluids is an important topic in biomechanics, often requiring the
use of computational tools to analyze problems with realistic geometries and material …

Cartilage tissue engineering is a promising approach to resurfacing osteoarthritic joints.
Existing techniques successfully engineer small-sized constructs with native levels of …