Genetic predisposition to multiple sclerosis (MS) only explains a fraction of the disease risk;
lifestyle and environmental factors are key contributors to the risk of MS. Importantly, these …

Immune cell function and metabolism are closely linked. Many studies have now clearly
demonstrated that alterations in cellular metabolism influence immune cell function and that …

Multiple sclerosis (MS) is more common in western countries with diet being a potential
contributing factor. Here we show that intermittent fasting (IF) ameliorated clinical course and …

Recent findings have provided a molecular basis for the combined contributions of
multifaceted risk factors for the onset of multiple sclerosis (MS). MS appears to start as a …

Growing empirical evidence suggests that nutrition and bacterial metabolites might impact
the systemic immune response in the context of disease and autoimmunity. We report that …

In the last decades, autoimmune diseases have experienced a dramatic increase in Western
countries. The involvement of environmental factors is strongly suspected to explain this rise …

Epigenetic modifications on DNA and histones regulate gene expression by modulating
chromatin accessibility to transcription machinery. Here we identify methionine as a key …

The last couple of decades have seen an explosion in our interest and understanding of the
role of vitamin D in the regulation of immunity. At the molecular level, the hormonal form of …

Abstract Purpose of Review This review seeks to examine current research related to the
role of diet in multiple sclerosis (MS). Recent Findings Recent research in preclinical …

Lifestyle and environmental factors potently influence the risk of multiple sclerosis (MS),
because genetic predisposition only explains a fraction of the risk increase. There is strong …