A Compressive Review about Taxol®: History and Future Challenges
Taxol®, which is also known as paclitaxel, is a chemotherapeutic agent widely used to treat
different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to …
different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to …
Long non-coding RNAs in the regulation of gene expression: physiology and disease
The identification of RNAs that are not translated into proteins was an important
breakthrough, defining the diversity of molecules involved in eukaryotic regulation of gene …
breakthrough, defining the diversity of molecules involved in eukaryotic regulation of gene …
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) as new tools for cancer therapy: first steps from bench to bedside
Non-coding RNAs represent a significant proportion of the human genome. After having
been considered as 'junk'for a long time, non-coding RNAs are now well established as …
been considered as 'junk'for a long time, non-coding RNAs are now well established as …
[HTML][HTML] LncRNA-miRNA axes in breast cancer: Novel points of interaction for strategic attack
Therapeutic effectiveness in breast cancer can be limited by the underlying mechanisms of
pathogenesis, including epithelial-mesenchymal transition (EMT), cancer stem cells (CSCs) …
pathogenesis, including epithelial-mesenchymal transition (EMT), cancer stem cells (CSCs) …
miRWalk2. 0: a comprehensive atlas of microRNA-target interactions
H Dweep, N Gretz - Nature methods, 2015 - nature.com
miRWalk2. 0 (http://zmf. umm. uni-heidelberg. de/mirwalk2) is a comprehensive archive,
supplying the largest available collection of predicted and experimentally verified microRNA …
supplying the largest available collection of predicted and experimentally verified microRNA …
Non-coding RNAs in cancer: Platforms and strategies for investigating the genomic “dark matter”
The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …
TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury
S Xu, J Wang, J Jiang, J Song, W Zhu, F Zhang… - Cell Death & …, 2020 - nature.com
Neuroinflammation plays a crucial role in the secondary phase of spinal cord injury (SCI),
and is initiated following the activation of toll-like receptor 4 (TLR4). However, the …
and is initiated following the activation of toll-like receptor 4 (TLR4). However, the …
Crosstalk between long non-coding RNAs, micro-RNAs and mRNAs: deciphering molecular mechanisms of master regulators in cancer
E López-Urrutia, LP Bustamante Montes… - Frontiers in …, 2019 - frontiersin.org
Cancer is a complex disease, and its study requires deep understanding of several
biological processes and their regulation. It is an accepted fact that non-coding RNAs are …
biological processes and their regulation. It is an accepted fact that non-coding RNAs are …
Functions of lncRNA HOTAIR in lung cancer
G Loewen, J Jayawickramarajah, Y Zhuo… - Journal of hematology & …, 2014 - Springer
Long non-coding RNAs (lncRNAs) govern fundamental biochemical and cellular processes.
lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through …
lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through …
Long non-coding RNA structure and function: is there a link?
A Zampetaki, A Albrecht, K Steinhofel - Frontiers in physiology, 2018 - frontiersin.org
RNA has emerged as the prime target for diagnostics, therapeutics and the development of
personalized medicine. In particular, the non-coding RNAs (ncRNAs) that do not encode …
personalized medicine. In particular, the non-coding RNAs (ncRNAs) that do not encode …