Regulation of Nuclear Factor-KappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis?

S Mirzaei, A Zarrabi, F Hashemi, A Zabolian, H Saleki… - Cancer Letters, 2021 - Elsevier
The nuclear factor-kappaB (NF-κB) signaling pathway is considered as a potential
therapeutic target in cancer therapy. It has been well established that transcription factor NF …

Therapeutic strategies to overcome cisplatin resistance in ovarian cancer

M Song, M Cui, K Liu - European journal of medicinal chemistry, 2022 - Elsevier
Ovarian cancer (OC) is one of the most common gynecologic tumors worldwide and one
with the highest mortality. Cisplatin (DDP) is the first platinum-based complex approved by …

Cell–cell communication: new insights and clinical implications

J Su, Y Song, Z Zhu, X Huang, J Fan, J Qiao… - Signal Transduction and …, 2024 - nature.com
Multicellular organisms are composed of diverse cell types that must coordinate their
behaviors through communication. Cell–cell communication (CCC) is essential for growth …

Dietary fiber in the prevention of obesity and obesity-related chronic diseases: From epidemiological evidence to potential molecular mechanisms

IS Waddell, C Orfila - Critical reviews in food science and nutrition, 2023 - Taylor & Francis
Obesity is a mostly preventable diet-related disease and currently a major challenge for
human populations worldwide. Obesity is a major risk factor for diseases such as type 2 …

Biological activities of essential oils: From plant chemoecology to traditional healing systems

J Sharifi-Rad, A Sureda, GC Tenore, M Daglia… - Molecules, 2017 - mdpi.com
Essential oils are complex mixtures of hydrocarbons and their oxygenated derivatives
arising from two different isoprenoid pathways. Essential oils are produced by glandular …

Natural polyphenols: An overview

M Abbas, F Saeed, FM Anjum, M Afzaal… - … Journal of Food …, 2017 - Taylor & Francis
Plant-derived functional foods are gaining considerable attention due to their safety and
therapeutic potentials. Research on plant-based functional foods presents several …

The relationship between gut microbiota and inflammatory diseases: the role of macrophages

J Wang, WD Chen, YD Wang - Frontiers in microbiology, 2020 - frontiersin.org
Gut microbiota, an integral part of the human body, comprise bacteria, fungi, archaea, and
protozoa. There is consensus that the disruption of the gut microbiota (termed “gut …

Therapeutic strategies to overcome taxane resistance in cancer

T Das, U Anand, SK Pandey, CR Ashby Jr… - Drug Resistance …, 2021 - Elsevier
One of the primary causes of attenuated or loss of efficacy of cancer chemotherapy is the
emergence of multidrug resistance (MDR). Numerous studies have been published …

Cyclin D1, cancer progression, and opportunities in cancer treatment

S Qie, JA Diehl - Journal of molecular medicine, 2016 - Springer
Mammalian cells encode three D cyclins (D1, D2, and D3) that coordinately function as
allosteric regulators of cyclin-dependent kinase 4 (CDK4) and CDK6 to regulate cell cycle …

Emerging role of human microbiome in cancer development and response to therapy: special focus on intestinal microflora

H Sadrekarimi, ZR Gardanova, M Bakhshesh… - Journal of translational …, 2022 - Springer
In recent years, there has been a greater emphasis on the impact of microbial populations
inhabiting the gastrointestinal tract on human health and disease. According to the …