Rates of alcohol use disorder (AUD) have increased in women by 84% over the past ten
years relative to a 35% increase in men. This substantive increase in female drinking is …

Neuroinflammation is a multifaceted physiological and pathophysiological response of the
brain to injury and disease. Given imaging findings of 18 kDa translocator protein (TSPO) …

Fibromyalgia (FM) is a poorly understood chronic condition characterized by widespread
musculoskeletal pain, fatigue, and cognitive difficulties. While mounting evidence suggests a …

Alcohol use disorder (AUD) is a widespread disease with limited treatment options.
Targeting the neuroimmune system is a new avenue for develo** or repurposing effective …

Introduction The 18-kDa translocator protein (TSPO) is increasingly recognized as a
molecular target for PET imaging of inflammatory responses in various central nervous …

As the professional phagocytes of the brain, microglia orchestrate the immunological
response and play an increasingly important role in maintaining homeostatic brain functions …

Addiction is a worldwide public health problem and this article reviews scientific advances in
identifying the role of neuroinflammation in the genesis, maintenance, and treatment of …

Abstract The use of Translocator Protein 18 kDa (TSPO) as a clinical neuroimaging
biomarker of brain injury and neuroinflammation has increased exponentially in the last …

A great deal of interest in psychiatric research is currently centered upon the pathogenic role
of inflammatory processes. Positron emission tomography (PET) using radiolabeled ligands …

Increasing evidence suggests a role of neuroinflammation in substance use disorders
(SUDs). This Review presents findings from neuroimaging studies assessing brain markers …