Pharmaceutical strategies of improving oral systemic bioavailability of curcumin for clinical application

Z Ma, N Wang, H He, X Tang - Journal of Controlled Release, 2019 - Elsevier
Curcumin (Cur), a natural compound from Curcuma longa Linn, has various of
pharmacological activities such as anti-cancer, anti-inflammatory, anti-oxidant, anti …

Curcumin-loaded mesoporous silica nanoparticles for drug delivery: synthesis, biological assays and therapeutic potential–a review

M Iranshahy, MY Hanafi-Bojd, SH Aghili, M Iranshahi… - RSC …, 2023 - pubs.rsc.org
Curcumin-loaded mesoporous silica nanoparticles (MSNs) have shown promise as drug
delivery systems to address the limited pharmacokinetic characteristics of curcumin …

Enhancing the oral bioavailability of curcumin using solid lipid nanoparticles

C Ban, M Jo, YH Park, JH Kim, JY Han, KW Lee… - Food Chemistry, 2020 - Elsevier
To control the oral bioavailability of curcumin, we fabricated solid lipid nanoparticles (SLNs)
using tristearin and polyethylene glycol (PEG) ylated emulsifiers. Lipolysis of prepared SLNs …

Evaluation of mesoporous silica nanoparticles for oral drug delivery–current status and perspective of MSNs drug carriers

J Florek, R Caillard, F Kleitz - Nanoscale, 2017 - pubs.rsc.org
The oral pathway is considered as the most common method for drug administration,
although many drugs, especially the highly pH-and/or enzymatic biodegradable peptide …

Curcumin-loaded mesoporous silica nanoparticles dispersed in thermo-responsive hydrogel as potential Alzheimer disease therapy

TC Ribeiro, RM Sábio, MT Luiz, LC de Souza… - Pharmaceutics, 2022 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive and
behavioral impairment. Curcumin-loaded mesoporous silica nanoparticles (MSN-CCM) can …

Curcumin-loaded mesoporous silica nanoparticles/nanofiber composites for supporting long-term proliferation and stemness preservation of adipose-derived stem …

S Mashayekhi, S Rasoulpoor, S Shabani… - International journal of …, 2020 - Elsevier
The present research aims to design and develop a sustained drug release system to
support the long-term proliferation of human adipose-derived stem cells (hADSCs) without …

Dual drug release mechanisms through mesoporous silica nanoparticle/electrospun nanofiber for enhanced anticancer efficiency of curcumin

L Xu, W Li, S Sadeghi‐Soureh… - … Research Part A, 2022 - Wiley Online Library
Electrospun nanofibers (NFs)‐based drug delivery approaches are of particular interest as a
hopeful implantable nanoplatform for localized cancer therapy and treating tissue defect …

Mesoporous silica incorporated PCL/Curcumin nanofiber for wound healing application

S Rathinavel, PS Korrapati, P Kalaiselvi… - European Journal of …, 2021 - Elsevier
Electrospinning, a recent fast-emerging technique highly applicable in the production of
nanofibers has gained vast recognition owing to its explicit applications in various domains …

Exploiting mesoporous silica nanoparticles as versatile drug carriers for several routes of administration

RM Sábio, AB Meneguin, AM dos Santos… - Microporous and …, 2021 - Elsevier
The exploitation of mesoporous silica nanoparticles (MSNs) as drug delivery systems has
grown exponentially due to their remarkable tunable properties, such as high surface area …

Fabrication of curcumin-loaded zein nanoparticles stabilized by sodium caseinate/sodium alginate: Curcumin solubility, thermal properties, rheology, and stability

Q Liu, C Han, Y Tian, T Liu - Process Biochemistry, 2020 - Elsevier
Curcumin is a polyphenol with multiple biological activities, but its extremely poor water
solubility severely limits its application in the food industry. The purposes of this work were to …