Abstract The interleukin-17 (IL-17) family comprises six members (IL-17A–17F), and
recently, all of its related receptors have been discovered. IL-17 was first discovered …

IL-17 cytokine family members have diverse biological functions, promoting protective
immunity against many pathogens but also driving inflammatory pathology during infection …

Fungal communities (the mycobiota) are an integral part of the gut microbiota, and the
disruption of their integrity contributes to local and gut-distal pathologies. Yet, the …

The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has
been implicated in multiple aspects of epithelial barrier function, including regulation of …

The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor regulating
adaptive and maladaptive responses toward exogenous and endogenous signals …

Klebsiella species cause a wide range of diseases including pneumonia, urinary tract
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …

Klebsiella pneumoniae causes a wide range of infections, including pneumonias, urinary
tract infections, bacteremias, and liver abscesses. Historically, K. pneumoniae has caused …

Crohn's disease (CD) is a chronic relapsing disorder of the gastrointestinal tract and
represents one of the main entities of inflammatory bowel disease (IBD). CD affects …

Epithelial regeneration is critical for barrier maintenance and organ function after intestinal
injury. The intestinal stem cell (ISC) niche provides Wnt, Notch and epidermal growth factor …

Increased understanding of the biology of interleukin 17 (IL-17) has revealed that this
cytokine is a central player in immunity at the sites most exposed to microorganisms …