Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease affecting up to 30% of the
general adult population. NAFLD encompasses a histological spectrum ranging from pure …

Acute pancreatitis (AP) is a common gastrointestinal disease and the leading cause of
hospital admission and healthcare burden among gastrointestinal disorders in many …

Lysosomal storage disorders (LSD) are a rare group of genetic disorders. The major LSDs
that cause liver dysfunction are disorders of sphingolipid lipid storage [Gaucher disease …

Bile acids are the main component of animal bile and are directly involved in the metabolic
process of lipids in vivo. Taurochenodeoxycholic acid (TCDCA) is the primary biologically …

Excessive accumulation of triacylglycerol is the common denominator of a wide range of
clinical pathologies of liver diseases, termed non-alcoholic fatty liver disease. Such …

Cryptogenic cirrhosis (CC) is defined as cirrhosis of unknown etiology despite extensive
clinical, laboratory and pathologic work-up, and constitutes approximately 5–10% of all …

Wolman disease is an ultrarare lysosomal storage disease caused by a mutation in the LIPA
gene. The clinical features of Wolman disease include early onset of vomiting, diarrhea …

Background Cholesterol ester storage disorder (CESD; OMIM: 278,000) was formerly
assumed to be an autosomal recessive allelic genetic condition connected to diminished …

Objective: Rare disease Background: Lysosomal acid lipase deficiency is a rare genetic
metabolic lipid storage disease, with a high morbidity, and mortality, in children and adults. It …

BACKGROUND Cholesteryl ester storage disease (CESD) is a rare genetic disease. Its
symptoms and severity are highly variable. CESD is a systemic disease that can lead to the …