[HTML][HTML] Targeting gut microbiota and metabolism as the major probiotic mechanism-An evidence-based review

T Ma, X Shen, X Shi, HA Sakandar, K Quan, Y Li… - Trends in Food Science …, 2023 - Elsevier
Background The human gut hosts complex microbial communities, which are linked to
health and disease. The gut microbiota is continuously reshaped by multiple environmental …

Effects of probiotics on gut microbiota: an overview

P Chandrasekaran, S Weiskirchen… - International journal of …, 2024 - mdpi.com
The role of probiotics in regulating intestinal flora to enhance host immunity has recently
received widespread attention. Altering the human gut microbiota may increase the …

Structure and hepatoprotective activity of Usp10/NF-κB/Nrf2 pathway-related Morchella esculenta polysaccharide

S Teng, Y Zhang, X **, Y Zhu, L Li, X Huang… - Carbohydrate …, 2023 - Elsevier
The water-soluble Morchella esculenta polysaccharide 2 (MEP2) was purified and isolated
from an aqueous extract of the Morchella esculenta fruiting bodies. MEP2, having a …

Bacteroides thetaiotaomicron ameliorates mouse hepatic steatosis through regulating gut microbial composition, gut-liver folate and unsaturated fatty acids …

H Li, XK Wang, M Tang, L Lei, JR Li, H Sun, J Jiang… - Gut …, 2024 - Taylor & Francis
Gut microbiota plays an essential role in the progression of nonalcoholic fatty liver disease
(NAFLD), making the gut-liver axis a potential therapeutic strategy. Bacteroides genus, the …

New insights into the molecular basis of alcohol abstinence and relapse in alcohol-associated liver disease

LA Diaz, GS Winder, L Leggio, JS Bajaj, R Bataller… - Hepatology, 2023 - journals.lww.com
Alcohol use disorder (AUD) remains a significant public health concern, affecting around 5%
of adults worldwide. Novel pathways of damage have been described during the last years …

Bacteroides and NAFLD: pathophysiology and therapy

J Zhang, J Zhou, Z He, H Li - Frontiers in microbiology, 2024 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver condition observed
globally, with the potential to progress to non-alcoholic steatohepatitis (NASH), cirrhosis …

Gut microbiome-brain-cirrhosis axis

ML Smith, JB Wade, J Wolstenholme, JS Bajaj - Hepatology, 2024 - journals.lww.com
Cirrhosis is characterized by inflammation, degeneration, and fibrosis of liver tissue. Along
with being the most common cause of liver failure and liver transplant, cirrhosis is a …

Galangin prevents against ethanol-induced intestinal barrier dysfunction and NLRP3 inflammasome activation via NF-κB/MAPK signaling pathways in mice and caco …

Y Zhao, B Li, J Liu, L Chen, H Teng - Journal of agricultural and …, 2024 - ACS Publications
The potential of natural phytochemicals in addressing ethanol-related public safety concerns
has been garnering attention. Galangin, a potent flavonoid renowned for its antioxidative …

The gut-liver axis perspective: Exploring the protective potential of polysaccharides from Cistanche deserticola against alcoholic liver disease

H Wang, J Yan, K Wang, Y Liu, S Liu, K Wu… - International Journal of …, 2024 - Elsevier
The primary objective of this study is to investigate the potential mechanism behind the
protective effect of Cistanche deserticola polysaccharides (CP) against alcoholic liver …

What are the common downstream molecular events between alcoholic and nonalcoholic fatty liver?

G Tarantino, V Citro - Lipids in Health and Disease, 2024 - Springer
Liver fat storage, also called hepatic steatosis, is increasingly common and represents a
very frequent diagnosis in the medical field. Excess fat is not without consequences. In fact …