In sharp contrast to many other cancer types, the incidence and mortality of endometrial
cancer continue to grow. This unfortunate trend is, in no small part, a result of the worldwide …

The increasing occurrence of obesity has become a significant public health concern.
Individuals with obesity have higher prevalence of heart disease, stroke, osteoarthritis …

Cardiovascular diseases are common for men and women but there are differences
between the sexes in terms of clinical symptoms, pathophysiology and response to the …

Globally, breast cancer is the most common cancer type and is one of the most significant
causes of deaths in women. To date, multiple clinical interventions have been applied …

Endometriosis is a chronic medical condition that affects around 6% to 10% of reproductive
age women. Pelvic pain, dysmenorrhea, and infertility are the most common presenting …

There is increasing recognition that environmental exposure to chemicals, such as
endocrine-disruptive chemicals (EDCs), contributes to the development of breast cancer …

Obesity and its associated metabolic dysregulation are established risk factors for many
cancers. However, the biologic mechanisms underlying this relationship remain …

Sex steroids are major promoters of the growth of breast and prostate cancers. This Review
by Poutanen et al. describes the development of treatments for these cancer types that act to …

Rearranged during transfection (RET) receptor tyrosine kinase was first identified over thirty
years ago as a novel transforming gene. Since its discovery and subsequent pathway …

Obesity is a prevalent global public health issue characterized by excess body fat. Adipose
tissue is now recognized as an important endocrine organ releasing an abundance of …