Loss of Myo19 increases metastasis by enhancing microenvironmental ROS gradient and chemotaxis

X Ren, P Shi, J Su, T Wei, J Li, Y Hu, C Wu - EMBO reports, 2024 - embopress.org
Tumor metastasis involves cells migrating directionally in response to external chemical
signals. Reactive oxygen species (ROS) in the form of H2O2 has been demonstrated as a …

A stable chemokine gradient controls directional persistence of migrating dendritic cells

T Quast, K Zölzer, D Guu, L Alvarez… - Frontiers in cell and …, 2022 - frontiersin.org
Navigation of dendritic cells (DCs) from the site of infection to lymphoid organs is guided by
concentration gradients of CCR7 ligands. How cells interpret chemokine gradients and how …

The Future of Genetic Disease Studies: Assembling an Updated Multidisciplinary Toolbox

S Ramadesikan, J Lee, RC Aguilar - Frontiers in Cell and …, 2022 - frontiersin.org
Over the past decades, we witnessed impressive progress in our understanding of the
mechanisms behind multiple genetic diseases including many considered to be “rare.” …

How Should Eukaryotic Chemotaxis be Measured?

L Tweedy, PA Thomason, RH Insall - bioRxiv, 2023 - biorxiv.org
Chemotaxis and directed cell migration are fundamentally important to eukaryotic biology.
To understand the mechanisms that drive such complex processes, informative and robust …

[BUCH][B] Analysis of immune cell migration in three dimensional environments

TL Czerwinski - 2024 - search.proquest.com
The immune system plays a key role in recognising and combating pathogens and tumour
cells in the body. To achieve their function, immune cells constantly patrol a connective …