Musculoskeletal and rheumatic diseases induced by immune checkpoint inhibitors: a review of the literature

D Benfaremo, L Manfredi, MM Luchetti… - Current drug …, 2018 - ingentaconnect.com
Background: Immune checkpoint inhibitors are a new promising class of antitumor drugs that
have been associated with a number of immune-related Adverse Events (AEs), including …

Frequency and distribution of various rheumatic disorders associated with checkpoint inhibitor therapy

N Abdel-Wahab, ME Suarez-Almazor - Rheumatology, 2019 - academic.oup.com
Immune checkpoint inhibitors have advanced the treatment paradigm of various cancers,
achieving remarkable survival benefits. However, a myriad of immune-related adverse …

Immune checkpoint inhibitors and the development of granulomatous reactions

CM Cornejo, P Haun, J English III… - Journal of the American …, 2019 - Elsevier
Immune checkpoint inhibitors (ICPIs) have emerged as a frontline treatment for a growing list
of malignancies. Disruption of the negative regulatory immune checkpoints by ICPIs has …

Immune checkpoint inhibitor-induced sarcoidosis-like granulomas

PH Rambhia, B Reichert, JF Scott, AN Feneran… - International Journal of …, 2019 - Springer
Immune checkpoint inhibitors targeting the cytotoxic T lymphocyte-associated antigen-4 and
programmed cell death-1 receptors have transformed the treatment of melanoma and other …

Sarcoid-like granulomatosis associated with immune checkpoint inhibitors in melanoma

A Melin, É Routier, S Roy, P Pradere, J Le Pavec… - Cancers, 2022 - mdpi.com
Simple Summary Granulomatosis is commonly observed in patients receiving immune
checkpoint inhibitors (ICIs) for melanoma and other cancers. Recognizing this reaction early …

Treatment of patients with cancer using PD‑1/PD‑L1 antibodies: Adverse effects and management strategies

G Sun, H Liu, X Shi, P Tan, W Tang… - International …, 2022 - spandidos-publications.com
In 2020, there were an estimated 19.3 million new cancer cases and close to 10 million
cancer deaths worldwide. Cancer remains one of the leading causes of death. In recent …

Challenges in sarcoidosis and sarcoid‐like reactions associated to immune checkpoint inhibitors: a narrative review apropos of a case

Z Apalla, C Kemanetzi, C Papageorgiou… - Dermatologic …, 2021 - Wiley Online Library
Sarcoidosis and sarcoid‐like reactions (SLRs) may develop in association with various
malignancies, as well as in association to certain oncologic drugs, including immune …

Immune checkpoint inhibitor–associated hypercalcaemia

H Izzedine, T Chazal, R Wanchoo… - Nephrology Dialysis …, 2022 - academic.oup.com
Immune checkpoint inhibitors (CPIs) have recently become a cornerstone for the treatment
of different advanced cancers. These drugs have the ability to reactivate the immune system …

Sarcoidosis related to checkpoint and BRAF/MEK inhibitors in melanoma

M Rubio-Rivas, C Moreira, J Marcoval - Autoimmunity Reviews, 2020 - Elsevier
Therapy for advanced melanoma has deeply changed in the last decade with the
introduction of checkpoint and BRAF/MEK inhibitors. Granulomatous reactions have been …

Granulomatous and sarcoid-like immune-related adverse events following CTLA4 and PD1 blockade adjuvant therapy of melanoma: a combined analysis of ECOG …

I Eljilany, A Noor, M Paravathaneni, I Yassine, SJ Lee… - Cancers, 2023 - mdpi.com
Simple Summary Immune checkpoint inhibitors (ICIs) can cause granulomatous and sarcoid-
like lesions (GSLs) in several organs, and limited data existing that adequately inform the …