The human macula uniquely concentrates three carotenoids: lutein, zeaxanthin, and meso-
zeaxanthin. Lutein and zeaxanthin must be obtained from dietary sources such as green …

The emergence of safe and functional eggs for consumer acceptance has gained focus. The
production of carotenoid-enriched eggs has received attention due to its multifunctional …

Patients with Tangier disease exhibit extremely low plasma HDL concentrations resulting
from mutations in the ATP-binding cassette, sub-family A, member 1 (ABCA1) protein …

Macrophage-specific Abca1 knock-out (Abca1–M/–M) mice were generated to determine the
role of macrophage ABCA1 expression in plasma lipoprotein concentrations and the innate …

The identification of defective structures in the ATP-binding cassette (ABC) transporters
ABCG5 and ABCG8 in patients with sitosterolemia suggests that these two proteins are an …

Yellow, orange, and red coloration is a fundamental aspect of avian diversity and serves as
an important signal in mate choice and aggressive interactions. This coloration is often …

Vertebrate pigmentation patterns are amongst the best characterised model systems for
studying the genetic basis of adaptive evolution. The wealth of available data on the genetic …

Purpose.: We tested variants in genes related to lutein and zeaxanthin status for association
with age-related macular degeneration (AMD) in the Carotenoids in Age-Related Eye …

Transport of phospholipids across cell membranes plays a key role in a wide variety of
biological processes. These include membrane biosynthesis, generation and maintenance …

Initial lipidation of apoA-I by hepatic ABCA1 is critical for plasma HDL formation because it
enables pre-β HDL to function more efficiently as a cholesterol acceptor for other pathways …