Apoptotic cell death in disease—Current understanding of the NCCD 2023
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …
Mitochondrial control of inflammation
Numerous mitochondrial constituents and metabolic products can function as damage-
associated molecular patterns (DAMPs) and promote inflammation when released into the …
associated molecular patterns (DAMPs) and promote inflammation when released into the …
NLRP3 inflammasome activation and cell death
The NLRP3 inflammasome is a cytosolic multiprotein complex composed of the innate
immune receptor protein NLRP3, adapter protein ASC, and inflammatory protease caspase …
immune receptor protein NLRP3, adapter protein ASC, and inflammatory protease caspase …
Exosomal miR-30d-5p of neutrophils induces M1 macrophage polarization and primes macrophage pyroptosis in sepsis-related acute lung injury
Y Jiao, T Zhang, C Zhang, H Ji, X Tong, R **a, W Wang… - Critical Care, 2021 - Springer
Abstract Background Polymorphonuclear neutrophils (PMNs) play an important role in
sepsis-related acute lung injury (ALI). Accumulating evidence suggests PMN-derived …
sepsis-related acute lung injury (ALI). Accumulating evidence suggests PMN-derived …
[HTML][HTML] Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
L Galluzzi, I Vitale, S Warren, S Adjemian… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune
response associated with immunological memory, provided they display sufficient …
response associated with immunological memory, provided they display sufficient …
The concept of intrinsic versus extrinsic apoptosis
L Lossi - Biochemical Journal, 2022 - portlandpress.com
Regulated cell death is a vital and dynamic process in multicellular organisms that maintains
tissue homeostasis and eliminates potentially dangerous cells. Apoptosis, one of the better …
tissue homeostasis and eliminates potentially dangerous cells. Apoptosis, one of the better …
FerrDb: a manually curated resource for regulators and markers of ferroptosis and ferroptosis-disease associations
N Zhou, J Bao - Database, 2020 - academic.oup.com
Ferroptosis is a mode of regulated cell death that depends on iron. Cells die from the toxic
accumulation of lipid reactive oxygen species. Ferroptosis is tightly linked to a variety of …
accumulation of lipid reactive oxygen species. Ferroptosis is tightly linked to a variety of …
The hallmarks of cancer immune evasion
According to the widely accepted" three Es" model, the host immune system eliminates
malignant cell precursors and contains microscopic neoplasms in a dynamic equilibrium …
malignant cell precursors and contains microscopic neoplasms in a dynamic equilibrium …
Roles of RIPK3 in necroptosis, cell signaling, and disease
Abstract Receptor-interacting protein kinase-3 (RIPK3, or RIP3) is an essential protein in the
“programmed” and “regulated” cell death pathway called necroptosis. Necroptosis is …
“programmed” and “regulated” cell death pathway called necroptosis. Necroptosis is …
Cell death in liver diseases: a review
Regulated cell death (RCD) is pivotal in directing the severity and outcome of liver injury.
Hepatocyte cell death is a critical event in the progression of liver disease due to resultant …
Hepatocyte cell death is a critical event in the progression of liver disease due to resultant …