Pseudomonas aeruginosa Biofilms

MTT Thi, D Wibowo, BHA Rehm - International journal of molecular …, 2020 - mdpi.com
Pseudomonas aeruginosa is an opportunistic human pathogen causing devastating acute
and chronic infections in individuals with compromised immune systems. Its highly notorious …

Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics

SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Epidemiology and treatment of multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosa infections

JP Horcajada, M Montero, A Oliver, L Sorlí… - Clinical microbiology …, 2019 - journals.asm.org
In recent years, the worldwide spread of the so-called high-risk clones of multidrug-resistant
or extensively drug-resistant (MDR/XDR) Pseudomonas aeruginosa has become a public …

Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance

SW Dickey, GYC Cheung, M Otto - Nature Reviews Drug Discovery, 2017 - nature.com
The rapid evolution and dissemination of antibiotic resistance among bacterial pathogens
are outpacing the development of new antibiotics, but antivirulence agents provide an …

Nanomedicine and advanced technologies for burns: Preventing infection and facilitating wound healing

MAM Jahromi, PS Zangabad, SMM Basri… - Advanced drug delivery …, 2018 - Elsevier
According to the latest report from the World Health Organization, an estimated 265,000
deaths still occur every year as a direct result of burn injuries. A widespread range of these …

[HTML][HTML] Pseudomonas aeruginosa: Infections and novel approaches to treatment “Knowing the enemy” the threat of Pseudomonas aeruginosa and exploring novel …

N Sathe, P Beech, L Croft, C Suphioglu, A Kapat… - Infectious medicine, 2023 - Elsevier
Pseudomonas aeruginosa is an aerobic Gram-negative rod-shaped bacterium with a
comparatively large genome and an impressive genetic capability allowing it to grow in a …

Antimicrobial resistance in the next 30 years, humankind, bugs and drugs: a visionary approach

M Bassetti, G Poulakou, E Ruppe, E Bouza… - Intensive care …, 2017 - Springer
Purpose To describe the current standards of care and major recent advances with regard to
antimicrobial resistance (AMR) and to give a prospective overview for the next 30 years in …

Pseudomonas aeruginosa Cytotoxins: Mechanisms of Cytotoxicity and Impact on Inflammatory Responses

SJ Wood, JW Goldufsky, MY Seu, AH Dorafshar… - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is one of the most virulent opportunistic Gram-negative bacterial
pathogens in humans. It causes many acute and chronic infections with morbidity and …

Strong immune responses and protection of PcrV and OprF-I mRNA vaccine candidates against Pseudomonas aeruginosa

X Wang, C Liu, N Rcheulishvili, D Papukashvili, F **e… - npj Vaccines, 2023 - nature.com
Pseudomonas aeruginosa (PA) is a leading cause of hospital-acquired and ventilator-
associated pneumonia. The multidrug-resistance (MDR) rate of PA is increasing making the …

Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections

S Wagner, R Sommer, S Hinsberger, C Lu… - Journal of medicinal …, 2016 - ACS Publications
Infections with Pseudomonas aeruginosa have become a concerning threat in hospital-
acquired infections and for cystic fibrosis patients. The major problem leading to high …