Tripartite motif (TRIM) proteins have been implicated in multiple cellular functions, including
antiviral activity. Research efforts so far indicate that the antiviral activity of TRIMs relies, for …

The TRIM/RBCC proteins are defined by the presence of the tripartite motif composed of a
RING domain, one or two B‐box motifs and a coiled‐coil region. These proteins are involved …

A functional genomic approach, based on systematic data gathering, was used to
characterize a family of proteins containing a tri partite m otif (TRIM). A total of 37 TRIM …

CONSTANS promotes flowering of Arabidopsis in response to long‐day conditions. We
show that CONSTANS is a member of an Arabidopsis gene family that comprises 16 other …

PML is a component of a multiprotein complex, termed nuclear bodies, and the PML protein
was originally discovered in patients suffering from acute promyelocytic leukaemia (APL) …

The biological significance of RBCC (N-terminal RING finger/B-box/coiled coil) proteins is
increasingly being appreciated following demonstrated roles in disease pathogenesis …

The gene MID1, the mutation of which causes X-linked Opitz G/BBB syndrome (OS, MIM
300000), encodes a microtubule-associated protein (MAP). We show that mutation of MID1 …

Familial Mediterranean fever (FMF) is a recessive disorder characterized by episodes of
fever and intense inflammation. FMF attacks are unique in their sensitivity to the microtubule …

As sequencing of the human genome nears completion, the genes that cause many human
diseases are being identified and functionally described. This has revealed that many …

Members of the TRIpartite interaction Motif (TRIM) family of E3 ligases have been shown to
exhibit antiviral activities. Here we report a near comprehensive screen for antiretroviral …