The therapeutic potential of anthocyanins: current approaches based on their molecular mechanism of action

B Salehi, J Sharifi-Rad, F Cappellini, Ž Reiner… - Frontiers in …, 2020 - frontiersin.org
Anthocyanins are natural phenolic pigments with biological activity. They are well-known to
have potent antioxidant and antiinflammatory activity, which explains the various biological …

The anti-inflammatory properties of phytochemicals and their effects on epigenetic mechanisms involved in TLR4/NF-κB-mediated inflammation

HA Saleh, MH Yousef, A Abdelnaser - Frontiers in immunology, 2021 - frontiersin.org
Innate immune response induces positive inflammatory transducers and regulators in order
to attack pathogens, while simultaneously negative signaling regulators are transcribed to …

Anti-diabetic effects of natural antioxidants from fruits

C Sun, Y Liu, L Zhan, GR Rayat, J **ao, H Jiang… - Trends in Food Science …, 2021 - Elsevier
Background Diabetes mellitus (DM), a chronic disease characterized by hyperglycemia, is
an increasing global health problem which is associated with various chronic diseases such …

Health benefits of cyanidin-3-glucoside as a potent modulator of Nrf2-mediated oxidative stress

S Rahman, S Mathew, P Nair, WS Ramadan… - …, 2021 - Springer
Berries are natural sources of anthocyanins, especially cyanidin-3-glucoside (C3G), and
exhibit significant antioxidant, antidiabetic, anti-inflammatory, and cytoprotective effects …

Anthocyanin actions at the gastrointestinal tract: Relevance to their health benefits

PI Oteiza, E Cremonini, CG Fraga - Molecular Aspects of Medicine, 2023 - Elsevier
Anthocyanins (AC) are flavonoids abundant in the human diet, which consumption has been
associated to several health benefits, including the mitigation of cardiovascular disease …

Proanthocyanidins and where to find them: A meta-analytic approach to investigate their chemistry, biosynthesis, distribution, and effect on human health

G Mannino, G Chinigò, G Serio, T Genova, C Gentile… - Antioxidants, 2021 - mdpi.com
Proanthocyanidins (PACs) are a class of polyphenolic compounds that are attracting
considerable interest in the nutraceutical field due to their potential health benefits …

[HTML][HTML] Polyphenols in fermented apple juice: Beneficial effects on human health

S Zhang, C Hu, Y Guo, X Wang, Y Meng - Journal of Functional Foods, 2021 - Elsevier
Chronic non-communicable diseases are one of the major human health challenges in the
21st century. Fermented apple juice rich in polyphenols has a beneficial effect on the …

The anthocyanins in black currants regulate postprandial hyperglycaemia primarily by inhibiting α-glucosidase while other phenolics modulate salivary α-amylase …

SK Barik, WR Russell, KM Moar, M Cruickshank… - The Journal of nutritional …, 2020 - Elsevier
The hypoglycaemic effects of two Ribes sp. ie, anthocyanin-rich black currants (BC) were
compared to green currants (GC), which are low in anthocyanins to establish which …

Targeting PI3K/Akt/mTOR signaling pathway by polyphenols: Implication for cancer therapy

M Mirza-Aghazadeh-Attari, EM Ekrami, SAM Aghdas… - Life sciences, 2020 - Elsevier
Cancer is one of the biggest challenges facing medicine and its cure is regarded to be the
Holy Grail of medicine. Therapy in cancer is consisted as various artificial cytotoxic agents …

Food matrix and macronutrient digestion

E Capuano, AEM Janssen - Annual review of food science and …, 2021 - annualreviews.org
Food digestion may be regarded as a physiological interface between food and health.
During digestion, the food matrix is broken down and the component nutrients and bioactive …