Alzheimer's disease associated with Down syndrome: a genetic form of dementia
Adults with Down syndrome develop the neuropathological hallmarks of Alzheimer's
disease and are at very high risk of develo** early-onset dementia, which is now the …
disease and are at very high risk of develo** early-onset dementia, which is now the …
Dementia in Down syndrome: unique insights for Alzheimer disease research
IT Lott, E Head - Nature Reviews Neurology, 2019 - nature.com
Virtually all adults with Down syndrome (DS) show the neuropathological changes of
Alzheimer disease (AD) by the age of 40 years. This association is partially due to …
Alzheimer disease (AD) by the age of 40 years. This association is partially due to …
Down syndrome
Trisomy 21, the presence of a supernumerary chromosome 21, results in a collection of
clinical features commonly known as Down syndrome (DS). DS is among the most …
clinical features commonly known as Down syndrome (DS). DS is among the most …
[HTML][HTML] Early alterations in cortical and cerebellar regional brain growth in Down Syndrome: An in vivo fetal and neonatal MRI assessment
PA Patkee, AA Baburamani, V Kyriakopoulou… - NeuroImage: Clinical, 2020 - Elsevier
Down Syndrome (DS) is the most frequent genetic cause of intellectual disability with a wide
spectrum of neurodevelopmental outcomes. At present, the relationship between structural …
spectrum of neurodevelopmental outcomes. At present, the relationship between structural …
Neurologic complications of Down syndrome: a systematic review
Down syndrome (DS) is one of the most well-recognized genetic disorders. Persons with DS
are known to have a variety of co-morbid medical problems, affecting nearly all organ …
are known to have a variety of co-morbid medical problems, affecting nearly all organ …
[HTML][HTML] The medical care of people with intellectual disability
T Sappok, A Diefenbacher… - Deutsches Ärzteblatt …, 2019 - ncbi.nlm.nih.gov
Background An estimated 1.5 million persons in Germany are intellectually disabled.
Persons with intellectual disability (ID) are especially vulnerable to somatic and mental …
Persons with intellectual disability (ID) are especially vulnerable to somatic and mental …
A 12‐week exercise programme has a positive effect on everyday executive function in young people with Down syndrome: a pilot non‐randomised controlled trial
N Shields, N Mizzi, K Buhlert‐Smith… - Journal of …, 2022 - Wiley Online Library
Background Exercise has the potential to reduce cognitive decline in people with Down
syndrome by maximising their cognitive function. The aim of the study was to determine the …
syndrome by maximising their cognitive function. The aim of the study was to determine the …
Down syndrome regression disorder: updates and therapeutic advances
JD Santoro, RA Filipink, NT Baumer… - Current Opinion in …, 2023 - journals.lww.com
Down syndrome regression disorder: updates and therapeutic a... : Current Opinion in
Psychiatry Down syndrome regression disorder: updates and therapeutic advances …
Psychiatry Down syndrome regression disorder: updates and therapeutic advances …
Donepezil—An updated review of challenges in dosage form design
L Sutthapitaksakul, CR Dass, P Sriamornsak - Journal of Drug Delivery …, 2021 - Elsevier
Donepezil hydrochloride (DPH) was first launched in 1997 as a choline esterase inhibitor
(ChEI). The USFDA has approved it for treatment of Alzheimer's disease since it effectively …
(ChEI). The USFDA has approved it for treatment of Alzheimer's disease since it effectively …
Down syndrome
Abstract Down syndrome (DS; Trisomy 21) is the most common chromosomal disorder in
humans. It has numerous associated neurologic phenotypes including intellectual disability …
humans. It has numerous associated neurologic phenotypes including intellectual disability …