Microtubule dynamics and their control are essential for the normal function and division of
all eukaryotic cells. This plethora of functions is, in large part, supported by dynamic …

The cytoskeleton and its components—actin, microtubules and intermediate filaments—
have been studied for decades, and multiple roles of the individual cytoskeletal …

Supramolecular polymerization can be controlled in space and time by chemical fuels. A
nonassembled monomer is activated by the fuel and subsequently self-assembles into a …

Cytoplasmic dynein 1 is an important microtubule-based motor in many eukaryotic cells.
Dynein has critical roles both in interphase and during cell division. Here, we focus on …

Microtubules have fundamental roles in many essential biological processes, including cell
division and intracellular transport. They assemble and disassemble from their two ends …

Life is characterized by a myriad of complex dynamic processes allowing organisms to grow,
reproduce, and evolve. Physical approaches for describing systems out of thermodynamic …

Myosin motors power movements on actin filaments, whereas dynein and kinesin motors
power movements on microtubules. The mechanisms of these motor proteins differ, but, in …

In multicellular systems, oriented cell divisions are essential for morphogenesis and
homeostasis as they determine the position of daughter cells within the tissue and also, in …

Fuelled by ATP hydrolysis, dyneins generate force and movement on microtubules in a
wealth of biological processes, including ciliary beating, cell division and intracellular …

Microtubules—which define the shape of axons, cilia and flagella, and provide tracks for
intracellular transport—can be highly bent by intracellular forces, and microtubule structure …