Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

The acronym ESKAPE includes six nosocomial pathogens that exhibit multidrug resistance
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …

Antimicrobial peptides in recent years have gained increased interest among scientists,
health professionals and the pharmaceutical companies owing to their therapeutic potential …

Motivation Bacterial resistance to antibiotics is a growing concern. Antimicrobial peptides
(AMPs), natural components of innate immunity, are popular targets for develo** new …

The antimicrobial peptide database (APD, http://aps. unmc. edu/AP/) is an original database
initially online in 2003. The APD2 (2009 version) has been regularly updated and further …

Antimicrobial peptides constitute one of the most promising alternatives to antibiotics since
they could be used to treat bacterial infections, especially those caused by multidrug …

The recent outbreaks of infectious diseases caused by multidrug-resistant pathogens have
sounded a piercing alarm for the need of new effective antimicrobial agents to guard public …

Multidrug-resistant bacteria are a severe threat to public health. Conventional antibiotics are
becoming increasingly ineffective as a result of resistance, and it is imperative to find new …

Highlights•Antibiotic resistance is a serious problem of our era.•Antimicrobial peptides are
important templates for develo** new antibiotics.•Both peptide discovery and application …

Despite the great strides in healthcare during the last century, some challenges still
remained unanswered. The development of multi-drug resistant bacteria, the alarming …