Pleasure is mediated by well-developed mesocorticolimbic circuitry and serves adaptive
functions. In affective disorders, anhedonia (lack of pleasure) or dysphoria (negative affect) …

Emotions are fundamental to our experience and behavior, affecting and motivating all
aspects of our lives. Scientists of various disciplines have been fascinated by emotions for …

Affective neuroscience aims to understand how affect (pleasure or displeasure) is created by
brains. Progress is aided by recognizing that affect has both objective and subjective …

Relatively little is known about the neuropathophysiology of binge-eating disorder (BED).
Here, the evidence from neuroimaging, neurocognitive, genetics, and animal studies are …

The mesocorticolimbic pathway is canonically known as the" reward pathway." Embedded
within the center of this circuit is the striatum, a massive and complex network hub that …

A specialized cubic-millimeter hotspot in the rostrodorsal quadrant of medial shell in nucleus
accumbens (NAc) of rats may mediate opioid enhancement of gustatory hedonic impact or …

A markedly reduced interest or pleasure in activities previously considered pleasurable is a
main symptom in mood disorder and psychosis and is often present in other psychiatric …

Dance has traditionally been viewed from a Eurocentric perspective as a mode of self-
expression that involves the human body moving through space, performed for the purposes …

Age has a major effect on brain volume. However, the normative studies available are
constrained by small sample sizes, restricted age coverage and significant methodological …

Background The psychostimulant properties of caffeine are reviewed and compared with
those of prototypical psychostimulants able to cause substance use disorders (SUD) …