Visible light. Part I: Properties and cutaneous effects of visible light

E Austin, AN Geisler, J Nguyen, I Kohli… - Journal of the American …, 2021 - Elsevier
Approximately 50% of the sunlight reaching the Earth's surface is visible light (400-700 nm).
Other sources of visible light include lasers, light-emitting diodes, and flash lamps. Photons …

Photoprotection according to skin phototype and dermatoses: practical recommendations from an expert panel

T Passeron, HW Lim, CL Goh, HY Kang… - Journal of the …, 2021 - Wiley Online Library
Increasing evidence on the impact of the different wavelengths of sunlight on the skin
demonstrates the need for tailored recommendations of sunscreen according to skin …

Porphyria

DM Bissell, KE Anderson… - New England Journal of …, 2017 - Mass Medical Soc
Each of the eight enzymes involved in porphyrin synthesis can be defective and can
produce a distinctive form of porphyria. The diagnosis of porphyria can be obscure and the …

Skin protection by carotenoid pigments

J Flieger, M Raszewska-Famielec… - International Journal of …, 2024 - mdpi.com
Sunlight, despite its benefits, can pose a threat to the skin, which is a natural protective
barrier. Phototoxicity caused by overexposure, especially to ultraviolet radiation (UVR) …

Metal-free photocatalytic cross-electrophile coupling enables C1 homologation and alkylation of carboxylic acids with aldehydes

S Bonciolini, A Pulcinella, M Leone, D Schiroli… - Nature …, 2024 - nature.com
In contemporary drug discovery, enhancing the sp3-hybridized character of molecular
structures is paramount, necessitating innovative synthetic methods. Herein, we introduce a …

[HTML][HTML] Update on trial registration 11 years after the ICMJE policy was established

DA Zarin, T Tse, RJ Williams… - New England Journal of …, 2017 - Mass Medical Soc
Update on Trial Registration 11 Years after the ICMJE Policy Was Established | New England
Journal of Medicine Skip to main content The New England Journal of Medicine homepage …

Clinical guide and update on porphyrias

U Stölzel, MO Doss, D Schuppan - Gastroenterology, 2019 - Elsevier
Physicians should be aware of porphyrias, which could be responsible for unexplained
gastrointestinal, neurologic, or skin disorders. Despite their relative rarity and complexity …

Visible light. Part II: photoprotection against visible and ultraviolet light

AN Geisler, E Austin, J Nguyen, I Hamzavi… - Journal of the American …, 2021 - Elsevier
Cutaneous photobiology studies have focused primarily on the ultraviolet portion of the solar
spectrum. Visible light (VL), which comprises 50% of the electromagnetic radiation that …

Structures of active melanocortin-4 receptor–Gs-protein complexes with NDP-α-MSH and setmelanotide

NA Heyder, G Kleinau, D Speck, A Schmidt… - Cell Research, 2021 - nature.com
Abstract The melanocortin-4 receptor (MC4R), a hypothalamic master regulator of energy
homeostasis and appetite, is a class A G-protein-coupled receptor and a prime target for the …

Targeting the central melanocortin system for the treatment of metabolic disorders

P Sweeney, LE Gimenez, CC Hernandez… - Nature Reviews …, 2023 - nature.com
A large body of preclinical and clinical data shows that the central melanocortin system is a
promising therapeutic target for treating various metabolic disorders such as obesity and …