Small leucine‐rich proteoglycans (SLRP s) are involved in a variety of biological and
pathological processes. This review focuses on their regulatory roles in matrix assembly …

Tendon consists of highly ordered type I collagen molecules that are grouped together to
form subunits of increasing diameter. At each hierarchical level, the type I collagen is …

Collagen constitutes one-third of the human proteome, providing mechanical stability,
elasticity, and strength to organisms and is the prime construction material in biology …

The small leucine-rich proteoglycans (SLRPs), decorin and biglycan, are key regulators of
collagen fibril and matrix assembly. The goal of this work was to elucidate the roles of …

The objective of this paper is to provide a review on some aspects of the mathematical and
computational modelling of skin biophysics, with special focus on constitutive theories based …

Connective tissue mechanical behavior is primarily determined by the composition and
organization of collagen. In ligaments and tendons, type I collagen is the principal structural …

The biomechanical properties of connective tissues play fundamental roles in how
mechanical interactions of the body with its environment produce physical forces at the …

The transparent cornea is the major refractive element of the eye. A finely controlled
assembly of the stromal extracellular matrix is critical to corneal function, as well as in …

Tendon ruptures are increasingly common, repair can be difficult, and healing is poorly
understood. Tissue engineering approaches often require expansion of cell numbers to …

Despite the critical role tendons play in transmitting loads throughout the musculoskeletal
system, little is known about the microstructural mechanisms underlying their mechanical …