Potassium channels are transmembrane proteins that selectively facilitate the flow of
potassium ions down an electrochemical gradient. These molecules have been studied in …

Normal cell-cycle progression is a crucial task for every multicellular organism, as it
determines body size and shape, tissue renewal and senescence, and is also crucial for …

Diffuse gliomas, particularly glioblastomas, are incurable brain tumours. They are
characterized by networks of interconnected brain tumour cells that communicate via Ca2+ …

Glioblastoma (GBM) is the most common and malignant form of primary brain tumor with a
median survival time of 14–16 months in GBM patients. Surgical treatment with …

Background and aims Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of
cancer-related death worldwide. Neurotransmitter-initiated signalling pathway is profoundly …

Potassium (K+) channels are highly regulated membrane proteins that control the potassium
ion flux and respond to different cellular stimuli. These ion channels are grouped into three …

All animal cells control their volume through a complex set of mechanisms, both to
counteract osmotic perturbations of the environment and to enable numerous vital biological …

Ion channels are abundantly expressed in both excitable and non-excitable cells, thereby
regulating the Ca 2+ influx and downstream signaling pathways of physiological processes …

Glioblastoma multiforme (GBM) is a diffuse brain tumor characterized by high infiltration in
the brain parenchyma rendering the tumor difficult to eradicate by neurosurgery. Efforts to …

Epigenomic changes are an important feature of malignant tumors. How tumor
aggressiveness is affected by DNA methylation of specific loci is largely unexplored. In …