Clinical translation of nanomedicine

Y Min, JM Caster, MJ Eblan, AZ Wang - Chemical reviews, 2015 - ACS Publications
Clinical Translation of Nanomedicine | Chemical Reviews ACS ACS Publications C&EN CAS
Find my institution Log In Chemical Reviews ACS Publications. Most Trusted. Most Cited. Most …

State-of-the-art in design rules for drug delivery platforms: lessons learned from FDA-approved nanomedicines

CM Dawidczyk, C Kim, JH Park, LM Russell… - Journal of Controlled …, 2014 - Elsevier
The ability to efficiently deliver a drug to a tumor site is dependent on a wide range of
physiologically imposed design constraints. Nanotechnology provides the possibility of …

Microtubule-binding agents: a dynamic field of cancer therapeutics

C Dumontet, MA Jordan - Nature reviews Drug discovery, 2010 - nature.com
Microtubules are dynamic filamentous cytoskeletal proteins composed of tubulin and are an
important therapeutic target in tumour cells. Agents that bind to microtubules have been part …

An imagable and photothermal" Abraxane-like" nanodrug for combination cancer therapy to treat subcutaneous and metastatic breast tumors.

Q Chen, C Liang, C Wang, Z Liu - Advanced Materials (Deerfield …, 2014 - europepmc.org
A new" Abraxane-like" nanotheranostic formulation self-assembled from three clinically
approved agents, human serum albumin, paclitaxel, and indocyanine green, is developed …

Minireview: nanoparticles and the immune system

BS Zolnik, Á González-Fernández, N Sadrieh… - …, 2010 - academic.oup.com
Today nanotechnology is finding growing applications in industry, biology, and medicine.
The clear benefits of using nanosized products in various biological and medical …

Current understanding of interactions between nanoparticles and the immune system

MA Dobrovolskaia, M Shurin, AA Shvedova - Toxicology and applied …, 2016 - Elsevier
The delivery of drugs, antigens, and imaging agents benefits from using nanotechnology-
based carriers. The successful translation of nanoformulations to the clinic involves thorough …

Protein nanoparticles as drug carriers in clinical medicine

MJ Hawkins, P Soon-Shiong, N Desai - Advanced drug delivery reviews, 2008 - Elsevier
Solvent-based delivery vehicles for chemotherapy agents have been instrumental in
providing a means for hydrophobic agents to be administered intravenously. These solvents …

Polymeric nanoparticles for cancer therapy

S Parveen, SK Sahoo - Journal of drug targeting, 2008 - Taylor & Francis
Cancer is an ever-increasing menace that needs to be curbed soon. Though chemotherapy
is successful to some extent, the main drawbacks of chemotherapy is the limited accessibility …

Mind the gap: a survey of how cancer drug carriers are susceptible to the gap between research and practice

DL Stirland, JW Nichols, S Miura, YH Bae - Journal of Controlled Release, 2013 - Elsevier
With countless research papers using preclinical models and showing the superiority of
nanoparticle design over current drug therapies used to treat cancers, it is surprising how …

Albumin-Based Cyanine Crizotinib Conjugate Nanoparticles for NIR-II Imaging-Guided Synergistic Chemophototherapy

Z Hu, R Li, X Cui, Z Chen - ACS Applied Materials & Interfaces, 2023 - ACS Publications
Colorectal cancer (CRC) is presently the third deadliest cancer in the world. This malignant
cancer usually precedes the progression of precancerous lesions, and it is challenging to …