This review will consider whether nitric oxide (NO) contributes to maternal systemic
vasodilation during pregnancy, regulates uterine and fetoplacental blood flow, and is …

Normal pregnancy is associated with reductions in total vascular resistance and arterial
pressure possibly due to enhanced endothelium-dependent vascular relaxation and …

Reduction in uterine perfusion and the ensuing placental ischemia during late pregnancy
have been proposed to trigger increases in systemic vascular resistance and pregnancy …

This review aims to provide a comprehensive summary of the mechanisms involved in the
physiological adaptation of the vasculature to pregnancy. Profound changes occur both …

Pregnancy-induced hypertension has been suggested to be mediated by several
mechanisms, including reduced nitric oxide (NO) synthesis. In this study, the effects of …

Placental ischemia during pregnancy is thought to release cytokines such as tumor necrosis
factor-α (TNF-α), which may contribute to the increased vascular resistance associated with …

To examine the possible mechanisms of the vasodilatation and blunted pressor responses
in late pregnancy, we have studied vascular reactivity of the in situ blood perfused …

Tumor necrosis factor-α (TNF-α) is elevated in the plasma of preeclamptic women and may
have a role in pregnancy-induced hypertension. However, whether the hemodynamic effects …

OBJECTIVE: We tested the hypothesis that during pregnancy the endothelium mediates the
blunted response to adrenergic vasoconstriction. STUDY DESIGN: Mesenteric resistance …

The sinoaortic baroreflex is one of the primary mechanisms that regulates blood pressure.
Decreased baroreflex sensitivity has been reported in preeclampsia. We sought to …