The current outbreak of monkeypox (MPX) infection has emerged as a global matter of
concern in the last few months. MPX is a zoonosis caused by the MPX virus (MPXV), which …

The recent outbreaks of avian influenza A (H5N1) virus, its expanding geographic
distribution and its ability to transfer to humans and cause severe infection have raised …

The advantage of oncolytic viruses (OV) in cancer therapy is their dual effect of directly
killing tumours while prompting anti-tumour immune response. Oncolytic parapoxvirus ovis …

Chimeric antigen receptor (CAR)–engineered T cell therapy for solid tumors is limited by the
lack of both tumor-restricted and homogeneously expressed tumor antigens. Therefore, we …

The efficacy and safety of biological molecules in cancer therapy, such as peptides and
small interfering RNAs (siRNAs), could be markedly increased if high concentrations could …

As the leading cause of death worldwide, viruses significantly affect global health. Despite
the rapid progress in human healthcare, there are few viricidal and antiviral therapies that …

Antiviral drugs have traditionally been developed by directly targeting essential viral
components. However, this strategy often fails due to the rapid generation of drug-resistant …

Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

Oncolytic viruses (OVs) as one promising antitumor methods have made important
contributions to tumor immunotherapy, which arouse increasing attention. They provide the …

Background JX-594 is a targeted oncolytic poxvirus designed to selectively replicate in and
destroy cancer cells with cell-cycle abnormalities and epidermal growth factor receptor …