Recent developments in the immunopathology of COVID‐19

H Zhang, Y Sun, Y Wang, D Yazici, D Azkur, I Ogulur… - Allergy, 2023 - Wiley Online Library
There has been an important change in the clinical characteristics and immune profile of
Coronavirus disease 2019 (COVID‐19) patients during the pandemic thanks to the …

Viral infection and airway epithelial immunity in asthma

SR Kim - International journal of molecular sciences, 2022 - mdpi.com
Viral respiratory tract infections are associated with asthma development and exacerbation
in children and adults. In the course of immune responses to viruses, airway epithelial cells …

[HTML][HTML] Regulation of angiotensin-converting enzyme 2 isoforms by type 2 inflammation and viral infection in human airway epithelium

N Stocker, U Radzikowska, P Wawrzyniak, G Tan… - Mucosal …, 2023 - Elsevier
SARS-CoV-2 enters human cells through its main receptor, angiotensin-converting enzyme
2 (ACE2), which constitutes a limiting factor of infection. Recent findings demonstrating …

Transcriptomics of rhinovirus persistence reveals sustained expression of RIG‐I and interferon‐stimulated genes in nasal epithelial cells in vitro

HH Ong, AK Andiappan, K Duan, J Lum, J Liu, KS Tan… - Allergy, 2022 - Wiley Online Library
Abstract Background Human rhinoviruses (HRVs) are frequently associated with asthma
exacerbations, and have been found in the airways of asthmatic patients. While HRV …

Regulation of mRNA transcripts, protein isoforms, glycosylation and spatial localization of ACE2 and other SARS-CoV-2-associated molecules in human airway …

N Stocker, U Radzikowska, P Wawrzyniak, G Tan… - bioRxiv, 2022 - biorxiv.org
SARS-CoV-2 infection continues to pose a significant life threat, especially in patients with
comorbidities. It remains unknown, if asthma or allergen-and virus-induced airway …

EV-A71 induced IL-1β production in THP-1 macrophages is dependent on NLRP3, RIG-I, and TLR3

HI Huang, CC Chio, JY Lin, CJ Chou, CC Lin… - Scientific Reports, 2022 - nature.com
Abstract Enterovirus A71 (EV-A71) is an emerging enterovirus that can cause neurological
complications. Enhanced serum IL-1β levels were observed in EV-A71 patients with severe …

Reply to Sokolowska and Radzikowska

C Woehlk - American Journal of Respiratory and Critical Care …, 2023 - atsjournals.org
We thank Sokolowska and Radzikowska for their insightful letter regarding our recent
research (1). We are pleased to hear of their interest and appreciate their kind words about …

New aspects of allergic mechanisms and innate immunity in asthma. Alarmins as upstream mediators of asthma inflammation.

S Ramu - 2023 - portal.research.lu.se
Asthma is a chronic inflammatory lung disease affecting over 300 million individuals
worldwide. Both respiratory viral infections and aeroallergens have been identified as …