NF-κB signaling has been discovered for nearly 40 years. Initially, NF-κB signaling was
identified as a pivotal pathway in mediating inflammatory responses. However, with …

Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Abstract Development of topical bioactive formulations capable of overcoming the low
bioavailability of conventional eye drops is critically important for efficient management of …

Since the discovery of the nuclear factor kappa B (NF-ĸB) transcription factor 36 years ago,
many studies have linked the NF-ĸB signaling pathway to pathological and physiological …

The cornea is unique because of its complete avascularity. Corneal neovascularization
(CNV) can result from a variety of etiologies including contact lens wear; corneal infections; …

Ocular surface neovascularization and its resulting pathological changes significantly alter
corneal refraction and obstruct the light path to the retina, and hence is a major cause of …

Ocular delivery is the most challenging aspect in the field of pharmaceutical research. The
major hurdle for the controlled delivery of drugs to the eye includes the physiological static …

Hepatic ischemia/reperfusion injury (IRI) is an unavoidable course in liver transplantation,
during which the immune response of inflammation plays a leading part. MicroRNA-450b-5p …

Abstract Development of chemoresistance in breast cancer patients greatly increases
mortality. Thus, understanding mechanisms underlying breast cancer resistance to …

Tumor associated macrophage (TAM)-based immunotherapy has been presented as a
promising strategy in cancer therapy. The combination of TAM-based immunotherapy with …