Much medical research is observational. The reporting of observational studies is often of
insufficient quality. Poor reporting hampers the assessment of the strengths and …

Although antiretroviral therapy for HIV infection prevents AIDS-related complications and
prolongs life, it does not fully restore health. Long-term treated patients remain at higher than …

Importance Antiretroviral therapy (ART) has improved life expectancy for individuals with HIV
infection, but recent data comparing life span and comorbidity-free years by HIV status are …

Gran parte de la investigación biomédica es de tipo observacional. Los informes de los
estudios observacionales a menudo poseen una calidad insuficiente, lo que dificulta la …

Importance The prevalence of cardiometabolic multimorbidity is increasing. Objective To
estimate reductions in life expectancy associated with cardiometabolic multimorbidity …

Objectives Life expectancy is an important indicator informing decision making in policies
relating to HIV‐infected people. Studies estimating life expectancy after starting combination …

Background: It is unknown if a survival gap remains between HIV-infected and HIV-
uninfected individuals with access to care. Methods: We conducted a cohort study within …

Age-associated comorbidities (cardiovascular and renal disease) were more prevalent
among HIV-positive compared with HIV-uninfected patients. Comorbidity was associated …

A low CD4/CD8 ratio in elderly HIV-uninfected adults is associated with increased morbidity
and mortality. A subset of HIV-infected adults receiving effective antiretroviral therapy (ART) …

Background. While inflammation predicts mortality in treated human immunodeficiency virus
(HIV) infection, the prognostic significance of gut barrier dysfunction and phenotypic T-cell …