Colorectal cancer (CRC), a leading cause of cancer-related death worldwide, evolves as a
result of the stepwise accumulation of a series of genetic and epigenetic alterations in the …

Abstract MicroRNA-34 (miR-34) has been reported to be dysregulated in various human
cancers and regarded as a tumor suppressive microRNA because of its synergistic effect …

Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …

The pathogenesis of cutaneous T-cell lymphoma (CTCL) remains elusive. Recent
discoveries indicate that the oncogenic microRNA miR-155 is overexpressed in affected skin …

Non-coding RNAs (ncRNAs) have recently become increasingly important in the study of
cellular metabolism and regulation such as development, proliferation, differentiation and …

Colorectal cancer (CRC) is associated with significant morbidity and mortality as many
patients are diagnosed with advanced stage disease. MicroRNAs are small, noncoding RNA …

Introduction: Many RNA species have been identified as important players in the
development of chronic diseases including cancer. Certain classes of regulatory RNAs such …

Colorectal cancer represents a leading cause of cancer death. MicroRNAs (miRNAs) are
small non-coding RNA molecules that have been extensively studied in tumours, since …

For two decades Vogelstein's model has been the paradigm for describing the sequence of
molecular changes within protein-coding genes that would lead to overt colorectal cancer …

Abstract MicroRNA-200c (miR200c) recently emerged as an important regulator of
tumorigenicity and cancer metastasis; however, its role in regulating multidrug resistance …