Genomics for antimicrobial resistance surveillance to support infection prevention and control in health-care facilities
Integration of genomic technologies into routine antimicrobial resistance (AMR) surveillance
in health-care facilities has the potential to generate rapid, actionable information for patient …
in health-care facilities has the potential to generate rapid, actionable information for patient …
Treatment approaches to Mycobacterium abscessus pulmonary disease
MR Holt, T Baird - Clinics in Chest Medicine, 2023 - chestmed.theclinics.com
Mycobacterium abscessus complex is the most common cause of rapid-grower
nontuberculous mycobacterial pulmonary disease (NTM-PD) and a significant contributor to …
nontuberculous mycobacterial pulmonary disease (NTM-PD) and a significant contributor to …
Conjugation of vancomycin with a single arginine improves efficacy against mycobacteria by more effective peptidoglycan targeting
J Brčić, A Tong, PA Wender… - Journal of medicinal …, 2023 - ACS Publications
Drug resistant bacterial infections have emerged as one of the greatest threats to public
health. The discovery and development of new antimicrobials and anti-infective strategies …
health. The discovery and development of new antimicrobials and anti-infective strategies …
Mutational spectra are associated with bacterial niche
As observed in cancers, individual mutagens and defects in DNA repair create distinctive
mutational signatures that combine to form context-specific spectra within cells. We …
mutational signatures that combine to form context-specific spectra within cells. We …
[HTML][HTML] Unraveling antibiotic resistance mechanisms in Mycobacterium abscessus: the potential role of efflux pumps
SE Mudde, JA Schildkraut, NC Ammerman… - Journal of Global …, 2022 - Elsevier
Objectives Mycobacterium abscessus is an opportunistic respiratory pathogen in patients
with underlying lung disease. It is infamously known for its low treatment success rates …
with underlying lung disease. It is infamously known for its low treatment success rates …
Modeling nontuberculous mycobacterial infections in zebrafish
The incidence of infections due to nontuberculous mycobacteria (NTM) has increased
rapidly in recent years, surpassing tuberculosis in developed countries. Due to inherent …
rapidly in recent years, surpassing tuberculosis in developed countries. Due to inherent …
Preclinical murine models to study lung infection with Mycobacterium abscessus complex
Mycobacterium abscessus is a non-tuberculous mycobacterium (NTM) able to cause
invasive pulmonary infections, named NTM pulmonary disease. The therapeutic approaches …
invasive pulmonary infections, named NTM pulmonary disease. The therapeutic approaches …
Genomic epidemiology of Mycobacterium abscessus in a Canadian cystic fibrosis centre
The Mycobacterium abscessus complex causes significant morbidity and mortality among
patients with Cystic Fibrosis (CF). It has been hypothesized that these organisms are …
patients with Cystic Fibrosis (CF). It has been hypothesized that these organisms are …
Molecular epidemiology of Mycobacterium abscessus isolates recovered from German cystic fibrosis patients
N Wetzstein, M Diricks, TA Kohl… - Microbiology …, 2022 - Am Soc Microbiol
Infections due to Mycobacterium abscessus are a major cause of mortality and morbidity in
cystic fibrosis (CF) patients. Furthermore, M. abscessus has been suspected to be involved …
cystic fibrosis (CF) patients. Furthermore, M. abscessus has been suspected to be involved …
Lipoarabinomannan modification as a source of phenotypic heterogeneity in host-adapted Mycobacterium abscessus isolates
Mycobacterium abscessus is increasingly recognized as the causative agent of chronic
pulmonary infections in humans. One of the genes found to be under strong evolutionary …
pulmonary infections in humans. One of the genes found to be under strong evolutionary …