Induced pluripotent stem cells (iPSCs) have the ability to differentiate into cardiomyocytes
(CMs). They are not only widely used in cardiac pharmacology screening, human heart …

Finding new strategies for the treatment of heart failures using stem cells has attracted a lot
of attention. Meanwhile, nanotechnology-based approaches to regenerative medicine …

A novel approach to treating heart failures was developed with the introduction of iPSC
technology. Knowledge in regenerative medicine, developmental biology, and the …

Stem cell-based therapy has emerged as an attractive method for regenerating and
repairing the lost heart organ. On other hand, poor survival and maintenance of the cells …

Human telomerase reverse transcriptase (hTERT) remains suppressed in most normal
somatic cells. Resulting erosion of telomeres leads eventually to replicative senescence …

Telomeres as the protective ends of linear chromosomes, are synthesized by the enzyme
telomerase (TERT). Critically short telomeres essentially contribute to aging-related …

Background Cryopreservation has been extensively applied to the long-term storage of a
diverse range of biological materials. However, no comprehensive study is currently …

The clinical effectiveness of human induced pluripotent stem cells (iPSCs) is highly
dependent on a few key quality characteristics including the generation of high quality cell …

Telomere shortening is associated with aging and age-associated diseases. Additionally,
telomere dysfunction resulting from telomerase gene mutation can lead to premature aging …

Telomere is guanine-rich DNA sequence with a protein complex known as shelterin present
at the chromosomal ends to protect it from destruction and is known to play a key role in …