Targeting the gut and tumor microbiota in cancer

EM Park, M Chelvanambi, N Bhutiani, G Kroemer… - Nature medicine, 2022 - nature.com
Microorganisms within the gut and other niches may contribute to carcinogenesis, as well as
sha** cancer immunosurveillance and response to immunotherapy. Our understanding of …

Predictive biomarkers of colon cancer immunotherapy: Present and future

W Hou, C Yi, H Zhu - Frontiers in immunology, 2022 - frontiersin.org
Immunotherapy has revolutionized colon cancer treatment. Immune checkpoint inhibitors
(ICIs) have shown clinical benefits for colon cancer patients, especially those with high …

[HTML][HTML] Akkermansia muciniphila and Faecalibacterium prausnitzii in Immune-Related Diseases

RMRA Effendi, M Anshory, H Kalim, RF Dwiyana… - Microorganisms, 2022 - mdpi.com
Probiotics and synbiotics are used to treat chronic illnesses due to their roles in immune
system modulation and anti-inflammatory response. They have been shown to reduce …

Cancer immunotherapy: Challenges and limitations

S Taefehshokr, A Parhizkar, S Hayati… - … -Research and Practice, 2022 - Elsevier
Although cancer immunotherapy has taken center stage in mainstream oncology inducing
complete and long-lasting tumor regression, only a subset of patients receiving treatment …

[HTML][HTML] Unlocking the potential of the human microbiome for identifying disease diagnostic biomarkers

R Hajjo, DA Sabbah, AQ Al Bawab - Diagnostics, 2022 - mdpi.com
The human microbiome encodes more than three million genes, outnumbering human
genes by more than 100 times, while microbial cells in the human microbiota outnumber …

[HTML][HTML] Microbiome bacterial influencers of host immunity and response to immunotherapy

Y Yousefi, KJ Baines, SM Vareki - Cell Reports Medicine, 2024 - cell.com
The gut microbiota influences anti-tumor immunity and can induce or inhibit response to
immune checkpoint inhibitors (ICIs). Therefore, microbiome features are being studied as …

[HTML][HTML] Exploring the gut microbiota and its potential as a biomarker in gliomas

D Aljarrah, N Chalour, A Zorgani, T Nissan… - Biomedicine & …, 2024 - Elsevier
Gut microbiome alterations are associated with various cancers including brain tumours
such as glioma and glioblastoma. The gut communicates with the brain via a bidirectional …

[HTML][HTML] Diet, microbiome, and cancer immunotherapy—A comprehensive review

M Szczyrek, P Bitkowska, P Chunowski, P Czuchryta… - Nutrients, 2021 - mdpi.com
The immune system plays a key role in cancer suppression. Immunotherapy is widely used
as a treatment method in patients with various types of cancer. Immune checkpoint blockade …

Probiotics in microbiome ecological balance providing a therapeutic window against cancer

N Sehrawat, M Yadav, M Singh, V Kumar… - Seminars in cancer …, 2021 - Elsevier
The gut microbiota composition and dietary factors in our food along with the use of
prebiotics and probiotics play an important role in the maintenance of human health. A well …

Gut mucosal microbiota profiles linked to colorectal cancer recurrence

RX Huo, YJ Wang, SB Hou, W Wang… - World journal of …, 2022 - pmc.ncbi.nlm.nih.gov
BACKGROUND Emerging evidence links gut microbiota to various human diseases
including colorectal cancer (CRC) initiation and development. However, gut microbiota …